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首页> 外文期刊>Journal of Medical Sciences >Relationship Between Volume Status and Blood Pressure in Children with End Stage Renal Disease on Chronic Hemodialysis
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Relationship Between Volume Status and Blood Pressure in Children with End Stage Renal Disease on Chronic Hemodialysis

机译：慢性血液透析终末期肾脏疾病患儿的血脂状况与血压的关系

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摘要

The aim of present study was to determine the effect of interdialytic fluid accumulation (or intradialytic fluid removal) on blood pressure in pediatric patients with End Stage Renal Disease (ESRD) on chronic hemodialysis. Fifty patients with end stage renal disease on maintenance hemodialysis were enrolled in the study. They included 32 males and 18 females; age ranged from 2-16 years. We determined the association of the intradialytic decrease in blood pressure with the intradialytic decrease in plasma volume and body weight. The intradialytic decrease in plasma volume was calculated by measuring the pre- and postdialysis plasma proteins using the following equation: ΔPV = (PVpre-PVpost)/PVpre = (TPpost-TPpre)/TPpost. We found a significant positive correlation between both intradialytic decrease in systolic, diastolic and mean blood pressure s and predialysis systolic, diastolic and mean blood pressure s versus the decrease in plasma volume and body weight. Also, the highest decrease in plasma volume and body weight was found in the first session of the week (longest interdialytic period) compared to the 2nd and 3rd sessions of the week. Volume status influences both predialysis and postdialysis blood pressure . The effect of volume status on blood pressure may be higher in pediatric population than adults.
机译：本研究的目的是确定在终末期肾病（ESRD）的小儿慢性血液透析患者中​​，透析液间的积聚（或透析液内的去除）对血压的影响。该研究招募了五十名维持性血液透析的终末期肾脏疾病患者。其中包括32男性和18女性。年龄从2-16岁不等。我们确定了血压内透析降低与血浆容量和体重透析内降低的关联。通过使用以下公式测量透析前和透析后血浆蛋白，计算出血浆内血浆体积的减少：ΔPV=（PV pre -PV post ）/ PV 前 =（TP 后 -TP 前）/ TP 后。我们发现，透析内收缩压，舒张压和平均血压s的降低与透析前收缩压，舒张压和平均血压s与血浆量和体重的降低之间存在显着的正相关。此外，与一周的第二和第三次相比，在一周的第一阶段（最长的透析间隔），血浆体积和体重的下降最大。容量状态会同时影响透析前和透析后的血压。体积状态对血压的影响在儿科人群中可能比成年人高。

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