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首页> 外文期刊>Journal of Medical Case Reports >Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report
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Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report

机译：复发性少突胶质细胞瘤的立体定向多疗程：一例报告

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Introduction High grade gliomas are an insidious disease associated with an extremely poor prognosis. The role of re-irradiation for recurrent gliomas is unclear but several retrospective studies have indicated mild toxicity and modest outcomes with this regimen. With subsequent progression, it is unclear what options remain and more radiotherapy is rarely offered for fear of surpassing normal central nervous system tissue tolerance and causing significant side effects without significant benefit. Case presentation In this report, we describe a 37-year-old Caucasian male initially diagnosed with a grade IV oligodendroglioma, who received multiple courses of re-irradiation and experienced a survival of 10 years with minimal cognitive or neurologic deficits. Conclusion Significant toxicity with multiple courses of radiation does not always occur. Re-irradiation should be considered in a salvage setting.
机译：引言高度​​神经胶质瘤是一种隐匿性疾病，预后极差。再次照射对复发性神经胶质瘤的作用尚不清楚，但一些回顾性研究表明该方案具有轻度毒性和适度的预后。随着随后的进展，目前尚不清楚还有哪些选择，并且由于担心超过正常的中枢神经系统组织耐受性并导致明显的副作用而无明显益处，很少提供更多的放射治疗。病例介绍在本报告中，我们描述了一名最初诊断为IV级少突胶质细胞瘤的37岁白人男性，他接受了多个疗程的重新照射，并经历了10年的生存，认知或神经功能缺损最少。结论并非总是会发生多道放射的明显毒性。应在打捞环境中考虑重新照射。

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