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首页> 外文期刊>Journal of Medical Sciences >Prevalence of Parvovirus B19 Infection in Successful and Unsuccessful Pregnancy in Zahedan, Southeast of Iran
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Prevalence of Parvovirus B19 Infection in Successful and Unsuccessful Pregnancy in Zahedan, Southeast of Iran

机译：细小病毒B19感染在伊朗东南部扎赫丹的成功和失败妊娠中的流行率

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To determine the seroprevalence of PVB19 infection in obstetric population, present research was conducted in Zahedan at the southeast of Iran from 2001-2002. In this case-control study, we assayed both virus specific anti-IgG and anti-IgM antibodies among 168 women with term pregnancy (controls) and 156 women with pregnancy loss at first and second trimester (cases) by ELISA method. PVB19Anti-IgG positive rate was 21.8% in pregnancy loss (case) and 20.8% in term pregnancy (control). Parvovirus B19 IgM antibody was detected in 10.3% of case and 6.5% in control. Although specific Parvovirus B19 IgG and IgM antibodies had no statistically significant difference between two groups by the age and parity, but our study showed that the prevalence of parvovirus B19 IgM antibody was higher in women with unsuccessful pregnancy. It is considerable, that high levels of IgM antibody probably support the association between PVB19 infection and unsuccess-pregnancy.
机译：为了确定产科人群PVB19感染的血清阳性率，本研究于2001-2002年在伊朗东南部的扎赫丹进行。在该病例对照研究中，我们通过ELISA方法在168名足月妊娠的妇女（对照组）和156名妊娠早孕和中期妊娠的妇女（病例）中检测了病毒特异性抗IgG和抗IgM抗体。妊娠流产（病例）和足月妊娠（对照）的PVB19抗-IgG阳性率为21.8％。细小病毒B19 IgM抗体检出率为10.3％，对照组为6.5％。尽管按年龄和性别，两组特定细小病毒B19 IgG和IgM抗体之间无统计学差异，但我们的研究表明，妊娠失败的女性中细小病毒B19 IgM抗体的患病率较高。相当大的是，高水平的IgM抗体可能支持PVB19感染与妊娠失败之间的关联。

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