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首页> 外文期刊>Journal of Molecular Biology Research >Chromosomal Q-Heterochromatin and Age in Human Population
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Chromosomal Q-Heterochromatin and Age in Human Population

机译：染色体Q-异染色质与人类年龄

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Individuals in the population differ from each other in number, location, size and intensity of fluorescence of chromosomal Q-heterochromatin regions (Q-HRs). It has been shown that human populations differ significantly as concerns this feature. The question remains open as to whether there exist differences between individuals belonging to different age groups. This fact is very important for understanding the possible biological role of the broad quantitative variability of chromosomal Q-HRs in human genome. The quantitative content of chromosomal Q-HRs was studied in individuals of Kazakh and Russian nationality from different age groups. It was shown that chromosomal Q-HRs are most numerous in the genome of neonates, while they are the least numerous in the genome of elderly subjects (aged 60 years and older). It is supposed that the lesser amount of Q-HRs in the genome of elderly subjects is due to the selective advantage in their survival to old age. The possible selective value of chromosomal Q-HRs is discussed.
机译：群体中的个体在染色体Q-异染色质区域（Q-HRs）的数量，位置，大小和荧光强度方面互不相同。已经表明，人口在这一特征上有很大的不同。关于不同年龄组的个人之间是否存在差异，问题尚待解决。这个事实对于理解人类基因组中染色体Q-HR的广泛定量变异的可能生物学作用非常重要。在不同年龄组的哈萨克人和俄罗斯人中研究了染色体Q-HRs的定量含量。结果表明，在新生儿基因组中染色体Q-HRs最多，而在老年受试者（60岁及以上）的基因组中染色体Q-HRs最少。据推测，老年受试者基因组中较少的Q-HRs是由于其在老年生存中的选择性优势。讨论了染色体Q-HRs的可能选择性值。

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