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首页> 外文期刊>Journal of Mid-Life Health >Etiological and endoscopic profile of middle aged and elderly patients with upper gastrointestinal bleeding in a Tertiary Care Hospital in North India: A retrospective analysis
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Etiological and endoscopic profile of middle aged and elderly patients with upper gastrointestinal bleeding in a Tertiary Care Hospital in North India: A retrospective analysis

机译：印度北部一家三级护理医院中，老年上消化道出血患者的病因和内窥镜检查：回顾性分析

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Background: Upper gastrointestinal (GI) bleeding is a common medical emergency associated with significant morbidity and mortality. The clinical presentation depends on the amount and location of hemorrhage and the endoscopic profile varies according to different etiology. At present, there are limited epidemiological data on upper GI bleed and associated mortality from India, especially in the middle and elderly age group, which has a higher incidence and mortality from this disease. Aim: This study aims to study the clinical and endoscopic profile of middle aged and elderly patients suffering from upper GI bleed to know the etiology of the disease and outcome of the intervention. Materials and Methods: Out of a total of 1790 patients who presented to the hospital from May 2015 to August 2017 with upper GI bleed, and underwent upper GI endoscopy, data of 1270 patients, aged 40 years and above, was compiled and analyzed retrospectively. Results: All the patients included in the study were above 40 years of age. Majority of the patients were males, with a male to female ratio of 1.6:1. The most common causes of upper GI bleed in these patients were portal hypertension-related (esophageal, gastric and duodenal varices, portal hypertensive gastropathy, and gastric antral vascular ectasia GAVE), seen in 53.62% of patients, followed by peptic ulcer disease (gastric and duodenal ulcers) seen in 17.56% of patients. Gastric erosions/gastritis accounted for 15.20%, and duodenal erosions were seen in 5.8% of upper GI bleeds. The in-hospital mortality rate in our study population was 5.83%. Conclusion: The present study reported portal hypertension as the most common cause of upper GI bleeding, while the most common endoscopic lesions reported were esophageal varices, followed by gastric erosion/gastritis, and duodenal ulcer.
机译：背景：上消化道（GI）出血是一种常见的医疗急症，其发病率和死亡率均很高。临床表现取决于出血的数量和位置，并且内窥镜检查根据病因的不同而不同。目前，关于印度的上消化道出血和相关死亡率的流行病学数据有限，尤其是在中老年人群中，该疾病的发病率和死亡率更高。目的：本研究旨在研究患有上消化道出血的中老年患者的临床和内窥镜检查，以了解该病的病因和干预结果。材料与方法：回顾性分析2015年5月至2017年8月就诊于上消化道出血并接受上消化道内镜检查的1790例患者的数据，对1270例年龄在40岁及以上的患者进行回顾性分析。结果：研究中包括的所有患者均超过40岁。多数患者为男性，男女之比为1.6：1。这些患者中上消化道出血的最常见原因是与门静脉高压有关的（食管，胃和十二指肠静脉曲张，门静脉高压性胃病和胃窦血管扩张性GAVE），在53.62％的患者中可见，其次是消化性溃疡病（胃溃疡）和十二指肠溃疡）的患者占17.56％。胃糜烂/胃炎占15.20％，十二指肠糜烂占上消化道出血的5.8％。我们研究人群的院内死亡率为5.83％。结论：本研究报告门静脉高压是上消化道出血的最常见原因，而最常见的内窥镜病变是食管静脉曲张，其次是胃糜烂/胃炎和十二指肠溃疡。

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