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首页> 外文期刊>Journal of Optometry >Symmetry of peripheral retinal nonperfusion in diabetic retinopathy by ischemic index
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Symmetry of peripheral retinal nonperfusion in diabetic retinopathy by ischemic index

机译：缺血指数对糖尿病视网膜病变周围视网膜非灌注的对称性

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Purpose Diabetic retinopathy is the leading cause of blindness among working-age adults in most developed countries. It affects eyes bilaterally and is generally believed to be symmetrical, yet there are few studies evaluating the symmetry of diabetic retinopathy. The purpose of the present study was to evaluate the symmetry of the amount of peripheral retinal ischemia in patients with diabetic retinopathy. Methods Ultra-widefield fluorescein angiography images were obtained on both eyes of 54 subjects, mean age 56.4 years, from an urban eye clinic. A single, high quality image from the arteriovenous phase of the angiogram of each eye was selected for analysis. The total area of gradable fundus and area of nonperfusion seen in the arteriovenous phase of the ultra-widefield fluorescein angiogram were determined. An ischemic index (ISI) was calculated by dividing the non-perfused retinal area by the total retinal area and multiplying by 100. Results The mean ISI OD was 11.27, mean ISI OS was 11.64. The mean absolute value (±SD) of ISI difference between OD and OS was 4.46?±?6.09. A difference in ISI of 10% or less was found in 92.6% of subjects. A statistically significant correlation was found in the ISI between right and left eyes ( r s ?=?0.80, p ?0.0001) and there was no statistically significant difference in ISI between the right and left eyes ( p =?0.85). Conclusion Asymmetrical retinopathy in diabetic patients is uncommon and additional pathological processes should be considered in the presence of asymmetric DR.
机译：目的在大多数发达国家，糖尿病性视网膜病是工作年龄成人失明的主要原因。它双侧影响眼睛，通常被认为是对称的，但是很少有研究评估糖尿病性视网膜病的对称性。本研究的目的是评估糖尿病性视网膜病变患者周围视网膜缺血量的对称性。方法从城市眼科诊所的54名平均年龄为56.4岁的受试者的双眼中获得超宽视野荧光素血管造影图像。从每只眼的血管造影的动静脉相中选择单个高质量图像进行分析。确定在超宽视野荧光素血管造影的动静脉期中可见的可分级眼底总面积和未灌注面积。通过将未灌注的视网膜面积除以总视网膜面积并乘以100来计算缺血指数（ISI）。结果平均ISI OD为11.27，平均ISI OS为11.64。 OD与OS之间的ISI差的平均绝对值（±SD）为4.46±±6.09。在92.6％的受试者中，ISI的差异为10％或更小。在左眼和右眼之间的ISI中发现了统计学上显着的相关性（r s == 0.80，p <= 0.0001），而在右眼和左眼之间的ISI没有统计学上的显着差异（p = = 0.85）。结论糖尿病患者不对称性视网膜病变不常见，存在不对称DR时应考虑其他病理过程。

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