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首页> 外文期刊>Journal of Orthopaedic Surgery Research >Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplasty
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Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplasty

机译：通过引流加引流钳关节内注射氨甲环酸，以减少非骨水泥全膝关节置换术中的失血

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Background Patients undergoing cementless total knee arthroplasty (TKA) sometimes suffer large blood loss. In a retrospective study, we explored whether postoperative intra-articular retrograde injection of tranexamic acid (TA) and leaving a drain clamp in place for 1?h reduced blood loss. Patients and methods Patients ( n =?140) treated with unilateral primary cementless TKA (posterior cruciate ligament retained) were divided into two groups: those who had an intra-articular injection of TA (1000?mg) and drain clamping for 1?h postoperatively (study group, n =?70) and those who were not given TA and did not undergo clamping of their drains (control group, n =?70). Postoperative total blood loss, volume of drainage, hemoglobin level, transfusion amounts and rates, D-dimer level at postoperative day (POD) 7, and complications were recorded. Results Total blood loss, total drainage, mean transfusion volume, and transfusion rates were lower in the study group than in controls ( P P P Conclusions Immediately postoperative intra-articular retrograde injection of TA and 1?h of drain-clamping effectively reduced blood loss and blood transfusion after cementless TKA. We believe that this method is simple, easy, and suitable for these patients.
机译：背景技术进行非骨水泥全膝关节置换术（TKA）的患者有时会出现大量失血。在一项回顾性研究中，我们探讨了术后关节腔内逆行注射氨甲环酸（TA）并留置引流钳1小时，以减少失血量。患者和方法将单侧原发性非骨水泥性TKA（保留后交叉韧带）的患者（n = 140）分为两组：关节内注射TA（1000mg）和引流钳持续1h的患者。术后（研究组，n = 70）和那些未给予TA且未进行引流钳的患者（对照组，n = 70）。记录术后总失血量，引流量，血红蛋白水平，输血量和比率，术后第7天D-二聚体水平（POD）以及并发症。结果研究组的总失血量，总引流量，平均输血量和输血率均低于对照组（PPP结论术后立即关节内逆行注射TA和钳吸引流1h小时可有效减少失血量和血液非骨水泥性TKA输注，我们相信这种方法简单，容易，并且适合这些患者。

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