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首页> 外文期刊>Journal of Pharmacopuncture >Quantitative Analyses of the Functional Constituents in SanYangSam and SanYangSanSam
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Quantitative Analyses of the Functional Constituents in SanYangSam and SanYangSanSam

机译：三阳山和三阳三山功能成分的定量分析

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Objective: SanYangSam and SanYangSanSam are traditional Korea-medical herbs that are grown from Panax ginseng C.A. Meyer. In our previous studies, we found that the functional compounds in SanYangSam and SanYangSanSam were different and depended on the type and the cultivation environment of ginseng. This study aimed to profile the functional constituents in SanYangSam and SanYangSanSam. Methods: To profile the functional aspects of the many compounds that have therapeutic activities in SanYangSam and SanYangSanSam extracts, we used liquid chromatography tandem mass spectrometry and quadrupole orthogonal acceleration time-of-flight mass spectrometry. Results: A total of four major compounds were detected; two of which were the natural flavonoids kaempferol and quercetin. Among others, two polyacetylene compounds, including panaxydol and panaxynol, were detected. Conclusion: In this study, we found that panaxydol, one of the polyacetylene constituents of ginseng, is a candidate anti-cancer agent in SanYangSam and SanYangSanSam pharmacopuncture. In addition, we found that the panaxydol levels in the SanYangSanSam extract were over 30 times those in the SanYangSam extract.
机译：目的：三养山药和三养山药是从人参C.A.种植的韩国传统草药。迈耶在我们以前的研究中，我们发现三阳山和三阳三山中的功能化合物是不同的，并且取决于人参的类型和栽培环境。这项研究旨在概述三阳山和三阳三山的功能成分。方法：为了描述许多在三阳三和三阳三七提取物中具有治疗活性的化合物的功能方面，我们使用了液相色谱串联质谱和四极杆正交加速飞行时间质谱。结果：总共检测到四种主要化合物。其中两种是天然黄酮类山ka酚和槲皮素。其中，检测到了两种聚乙炔化合物，包括人参醛和人参炔醇。结论：在这项研究中，我们发现人参中的聚乙炔成分之一的人参吡喃酮是三阳山和三阳三山药物针刺中的候选抗癌药。此外，我们发现三阳三山提取物中的人参醛水平是三阳山提取物中的三倍以上。

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