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首页> 外文期刊>Journal of Rural and Remote Environmental Health >RISK FACTORS FOR ASTHMA IN IRAQI CHILDREN
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RISK FACTORS FOR ASTHMA IN IRAQI CHILDREN

机译：伊拉克儿童哮喘的危险因素

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Background: Although a large number of studies of asthma had been conducted, the etiology of childhood asthma is not yet established. Both life style factors and environmental exposure during early life may play important roles. Objective: To evaluate the risk factors for asthma in Iraqi primary school children. Patients and Methods: The sample consisted of 2875 children, who were between 11 and 14 years of age at the time of enrollment in the Regional Study of Asthma and Allergies in Childhood (RSAAC) and were subsequently followed up at their schools. Results: The prevalence of asthma when assessed by interview was 7.2% [95% confidence interval (CI) 6.3% - 8.3%], while it was 8.9% [95% CI 7.9 % - 10.0%] when assessed by clinical examination. There was no significant difference between the prevalence of asthma in males and females. Exposure to wood or oil smoke (Odds-ratio (OR)=2.40, 95% CI 1.84–3.17; P<0.001); cats and dogs (OR=2.95, 95% CI 2.15–4.04; P<0.001); herbicides and /or pesticides (OR=1.68, 95% CI 1.16–2.43; P=0.005); farm animals, farm crops or dust (exposure to animals OR= 2.97, 95% CI 2.02–4.37; P<0.001; exposure to farm crops (OR=2.17, 95% CI 1.33–3.55; P=0.002); and breastfeeding (OR=8.5, 95% CI 6.10-11.84; P<0.001) were significantly associated with asthma. Family history of asthma (OR=4.11, 95% CI 3.16-5.34; P<0.001) and atopy (OR=2.33, 95% CI 1.79-3.04; P<0.001) were associated with an increased prevalence of asthma. In addition, family history of smoking was associated with asthma (OR=1.52, 95% CI 1.17-1.97; P=0.001). Presence of skin problems (OR=2.40, 95% CI 1.63-3.55; P<0.001), gastro intestinal problems (OR=5.64, 95% CI 2.23-14.25; P<0.001) and food allergy (OR=6.08, 95% CI 2.96-12.52; P<0.001) were significantly associated with asthma in childhood. Maternal education (p<0.001) and social status (p=0.001) may be a risk markers for asthma in childhood. Conclusion: These results suggest that both environmental exposure and lifestyle factors are important risk factors for childhood asthma in Iraqi children. Both indoor and outdoor environmental exposure may play a crucial role in the etiology of childhood asthma.
机译：背景：尽管已经进行了大量的哮喘研究，但儿童哮喘的病因尚未建立。生活方式因素和早期生活中的环境暴露都可能起重要作用。目的：评估伊拉克小学生哮喘的危险因素。患者和方法：样本由2875名儿童组成，这些儿童在入组《儿童哮喘和过敏性区域研究》（RSAAC）时的年龄为11至14岁，并随后在其学校中接受随访。结果：通过访谈评估的哮喘患病率为7.2％[95％置信区间（CI）6.3％-8.3％]，而通过临床检查评估为8.9％[95％CI 7.9％-10.0％]。男性和女性的哮喘患病率之间无显着差异。暴露于木材或油烟中（几率（OR）= 2.40，95％CI 1.84–3.17; P <0.001）;猫和狗（OR = 2.95，95％CI 2.15–4.04; P <0.001）;除草剂和/或农药（OR = 1.68，95％CI 1.16–2.43; P = 0.005）;农场动物，农作物或粉尘（动物暴露OR = 2.97，95％CI 2.02–4.37; P <0.001;农作物暴露（OR = 2.17，95％CI 1.33–3.55; P = 0.002）;以及母乳喂养（ OR = 8.5，95％CI 6.10-11.84; P <0.001）与哮喘显着相关;哮喘家族史（OR = 4.11，95％CI 3.16-5.34; P <0.001）和特应性（OR = 2.33，95％） CI 1.79-3.04; P <0.001）与哮喘的患病率增加有关;此外，吸烟家族史与哮喘有关（OR = 1.52，95％CI 1.17-1.97; P = 0.001）。 （OR = 2.40，95％CI 1.63-3.55; P <0.001），肠胃问题（OR = 5.64，95％CI 2.23-14.25; P <0.001）和食物过敏（OR = 6.08，95％CI 2.96-12.52 ; P <0.001）与儿童哮喘显着相关;母体教育（p <0.001）和社会地位（p = 0.001）可能是儿童哮喘的危险标志结论：这些结果表明环境暴露和生活方式因素是儿童哮喘的重要危险因素在伊拉克儿童中。室内和室外环境暴露均可能在儿童哮喘的病因中起关键作用。

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