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首页> 外文期刊>Journal of Sexually Transmitted Diseases >Pharyngeal Gonorrhoea in Women: An Important Reservoir for IncreasingNeisseria gonorrhoeaPrevalence in Urban Australian Heterosexuals?
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Pharyngeal Gonorrhoea in Women: An Important Reservoir for IncreasingNeisseria gonorrhoeaPrevalence in Urban Australian Heterosexuals?

机译：女性咽部淋病：在澳大利亚城市异性恋者中增加淋病奈瑟氏球菌患病率的重要水库吗？

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We aim to characterize sexual behavioral aspects of heterosexualNeisseria gonorrhoea(NG) acquisition in two Sexually Transmitted Diseases clinics in Sydney, Australia, in 2008–2012. Of 167 NG cases, 102 were heterosexually acquired with a trend of increasing NG prevalence in heterosexuals from 1.1% (95% CI 0.6–2.1) in 2008 to 3.0% (95% CI 2.0–4.0) in 2012 (P=0.027). Of heterosexual male cases, unprotected fellatio was the likely sexual activity for NG acquisition in 21/69 (30.4%) and commercial sex work (CSW) contact the likely source in 28/69 (40.6%). NG prevalence overall in CSW (2.2%) was not significantly higher than in non-CSW (1.2%) (P=0.15), but in 2012 there was a significant increase in NG prevalence in CSW (8.6%) compared to non-CSW (1.6%) (P<0.001). Pharyngeal NG was found in 9/33 (27.3%) female cases. Decreased susceptibility to ceftriaxone (MIC ≥ 0.03 mg/L) occurred in 2.5% NG isolates, none heterosexually acquired. All were azithromycin susceptible. A significant trend of increasing prevalence of heterosexual gonorrhoea in an urban Australian STD clinic setting is reported. We advocate maintenance of NG screening in women, including pharyngeal screening in all women with partner change who report fellatio, as pharyngeal NG may be an important reservoir for heterosexual transmission. Outreach to CSW should be enhanced.
机译：我们的目标是在2008年至2012年间，在澳大利亚悉尼的两家性传播疾病诊所中，描述异性性淋病奈瑟氏球菌（NG）收购的性行为方面。在167例NG病例中，有102例是异性恋，异性恋中的NG患病率从2008年的1.1％（95％CI 0.6-2.1）增加到2012年的3.0％（95％CI 2.0-4.0）（P = 0.027）。在异性恋男性病例中，未受保护的口交是21/69（30.4％）可能发生的NG采集性行为，而商业性工作（CSW）可能是28/69（40.6％）的来源。 CSW的整体NG患病率（2.2％）并不明显高于非CSW的（1.2％）（P = 0.15），但2012年CSW的NG患病率（8.6％）与非CSW相比显着增加（1.6％）（P <0.001）。在9/33（27.3％）女性病例中发现了咽部NG。 2.5％NG分离株对头孢曲松的敏感性降低（MIC≥0.03 mg / L），没有异性获得。所有的人都对阿奇霉素敏感。据报道，在澳大利亚城市性病门诊中，异性淋病的患病率呈显着上升趋势。我们建议维持妇女的NG筛查，包括对所有有口交的伴侣变化的女性进行咽部筛查，因为这些咽部NG可能是异性传播的重要来源。与CSW的联系应加强。

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