Primary lung cancer presenting as metastasis to the big toe

A Tahir; G Antunes; I Mohamed; S Nicholson

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Primary lung cancer presenting as metastasis to the big toe

机译：转移至大脚趾的原发性肺癌

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A 62-year-old man presented with a 6-week history of shortness of breath, weight loss and painful swelling of the great toe. Examination elicited an ulcerated swelling of the right great toe, thought to be an ingrowing toenail. Chest ‘crackles' and an enlarged supraclavicular lymph node were detected. Biopsies of the toe swelling and bronchi both showed squamous cell carcinoma, confirmed radiologically as stage IV lung cancer. The patient was referred for palliative amputation of the toe. Cancer metastases to the digits may arise in bone, before enlarging to invade skin, or arise in skin first. 20-60% of cutaneous metastases present before or at the same time as the primary lung tumour. Cutaneous metastases and those in the digits indicate very poor prognosis. Their prompt diagnosis and management can dramatically improve a patient's quality of life and should be strived for.

机译：一名62岁的男子有6周的呼吸急促，体重减轻和大脚趾肿痛的病史。检查引起右大脚趾溃疡肿胀，被认为是向内生长的脚趾甲。发现胸部“裂”和锁骨上淋巴结肿大。脚趾肿胀和支气管活检均显示鳞状细胞癌，经放射学证实为IV期肺癌。该患者因姑息性截肢而被转诊。转移到手指的癌转移可能先于骨骼出现，然后才扩大到侵犯皮肤，或者首先发生于皮肤。在原发性肺肿瘤发生之前或同时出现20-60％的皮肤转移。皮肤转移和数字转移表明预后很差。他们的迅速诊断和管理可以极大地改善患者的生活质量，应该为此而努力。

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《Journal of Surgical Case Reports》 |2011年第12期|共1页
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A Tahir; G Antunes; I Mohamed; S Nicholson;
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中图分类临床医学;
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6. Primary lung cancer presenting as metastasis to the big toe [O] . S Nicholson, I Mohamed, A Tahir, 2011

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7. A novel differential diagnostic model for multiple primary lung cancer: Differentially-expressed gene analysis of multiple primary lung cancer and intrapulmonary metastasis [O] . DALI CHEN, LONGYONG MEI, YUBIN ZHOU, 2015

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Primary lung cancer presenting as metastasis to the big toe

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