Central Giant Cell Granulomas (CGCG) of the jaw are uncommon benign lesions which usually occur in the mandible in young adults. Here we present a case report of a 45-year-old woman who presented with a 5-month history of right nasal obstruction secondary to a large maxillary CGCG. The age, symptoms at presentation, location and radiographic features were not pathognomonic for this lesion. This case helps to demonstrate the wide variation in the clinical, radiological and histopathological features of CGCC and provides an update in current treatment concepts.
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