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首页> 外文期刊>Journal of the Canadian Academy of Child and Adolescent Psychiatry >Mental Health Problems in Children with Prader-Willi Syndrome
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Mental Health Problems in Children with Prader-Willi Syndrome

机译：普拉德-威利综合症儿童的心理健康问题

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Background: Prader-Willi Syndrome (PWS) is a genetically determined neurodevelopmental disorder, which occurs in approximately one in 22000 births. Aims: This study aimed to investigate psychiatric characteristics of children diagnosed with PWS compared with an age-, gender- and IQ-matched control group. The parents of children with PWS were assessed for psychological distress in comparison to the parents of the control group. Methodological limitations identified in previous studies were addressed in the present study. Methods: Psychiatric problems were evaluated in a sample of children with genetically confirmed PWS and an age- and IQ-matched control group using the Child Behaviour Checklist 6–18. Parental psychological distress for both groups was evaluated with the Brief Symptom Inventory. Results: Children with PWS had more severe somatic, social, and thought problems, and were more withdrawn-depressed in comparison to controls. Borderline difficulties were detected for the affective, somatic, and attention deficit-hyperactivity CBCL DSM-orientated subscales in the PWS group. Parents of PWS children, in comparison to controls, had more somatization, phobic anxiety, obsessive-compulsive, and anxiety problems. Conclusions: PWS represents a complex psychological disorder with multiple areas of disturbances.
机译：背景：普拉德-威利综合症（PWS）是一种遗传确定的神经发育障碍，大约每22000例新生儿中就有一个发生。目的：本研究旨在调查与年龄，性别和智商匹配的对照组相比，诊断为PWS的儿童的精神病学特征。与对照组的父母相比，对PWS儿童的父母进行了心理困扰评估。本研究解决了先前研究中确定的方法学局限性。方法：使用儿童行为检查表6-18，对经遗传学确诊的PWS患儿以及年龄和智商匹配的对照组的儿童进行精神病学评估。用简短症状量表评估两组父母的心理困扰。结果：与对照组相比，PWS患儿的躯体，社交和思想问题更为严重，并且对抑郁的抑郁程度更高。在PWS组中，针对情感性，躯体性和注意缺陷多动性CBCL DSM取向的次级量表发现了边界困难。与对照组相比，PWS儿童的父母有更多的躯体化，恐惧症，强迫症和焦虑症。结论：PWS代表了一种复杂的心理障碍，具有多个障碍区域。

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