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首页> 外文期刊>Journal of Young Pharmacists >Evaluation of Antimicrobial Activities of Garcinia latissima Miq. Stem Bark Extract
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Evaluation of Antimicrobial Activities of Garcinia latissima Miq. Stem Bark Extract

机译：藤黄的抗菌活性评价。茎皮提取物

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Introduction: To evaluate the antimicrobial activities of hexane, ethyl acetate, and methanol extracts from the stem bark of Garcinia latissima Miq. Method: The G. latissima Miq. was collected from Bogor. This study uses multilevel maceration extraction methods. The antimicrobial activity was determined by the good diffusion method and the broth dilution method. Result: The ethyl acetate extracts of stem bark were active against Bacillus subtilis, aeruginosa Staphylococcus aureus, and Ps aeruginosa, and virtually inactive against Escherichia coli, Candida albicans, and Trichophyton mentagrophytes. The methanol extracts of stem bark were active against B. subtilis and S. aureus, and virtually inactive against E. coli, P. aeroginosa, C. albicans, and T. mentagrophytes. The hexane extracts of stem bark were inactive against B. subtilis, S. aureus, E. coli, P. aeroginosa, C. albicans, and T. mentagrophytes. The 2% methanol extracts of G. latissima Miq. stem bark showed the maximum zone of inhibition against B. subtilis (10.70±0.638 mm), followed by the methanol extracts of G. latissima Miq. stem bark against S. aureus (10.38±0.653 mm). 2% Ethyl acetate extracts of G. latissima Miq. stem bark exhibited a maximum zone of inhibition against B. subtilis (10.35±0.867 mm) followed by P. aeruginosa (10.07±0.971 mm). The results of the antibacterial activity showed that the MeOH extract of G. latissima Miq. stem bark exhibited activities against B. subtilis (MIC/MBC = 625 ppm/2500 ppm)and S. aureus (MIC/MBC = 2500 ppm/5000 ppm). The ethyl acetate extract of G. latissima Miq. stem bark exhibited activities against P. aeruginosa (MIC/ MBC = 5000 ppm/5000 ppm) and B. subtilis (MIC/MBC > 5000 ppm/5000 ppm). Conclusion: The results of the present study revealed most valuable information and also support the continued sustainable use of G. latissima Miq. stem barks in a traditional system of medicine.
机译：简介：为了评估藤黄（Garcinia latissima Miq）茎皮中己烷，乙酸乙酯和甲醇提取物的抗菌活性。方法：G。latissima Miq。是从茂物收集的。本研究使用多级浸软提取方法。通过良好扩散法和肉汤稀释法测定抗菌活性。结果：茎皮的乙酸乙酯提取物对枯草芽孢杆菌，铜绿金黄色葡萄球菌和铜绿假单胞菌具有活性，而对大肠杆菌，白色念珠菌和薄荷癣菌几乎没有活性。茎皮的甲醇提取物对枯草芽孢杆菌和金黄色葡萄球菌有活性，而对大肠杆菌，铜绿假单胞菌，白色念珠菌和薄荷茶则几乎没有活性。茎皮的己烷提取物对枯草芽孢杆菌，金黄色葡萄球菌，大肠杆菌，铜绿假单胞菌，白色念珠菌和薄荷茶（T. mentagrophytes）没有活性。 G. latissima Miq的2％甲醇提取物。茎皮显示出对枯草芽孢杆菌的最大抑制区（10.70±0.638 mm），其次是G. latissima Miq的甲醇提取物。茎皮对金黄色葡萄球菌（10.38±0.653 mm）。 G. latissima Miq的2％乙酸乙酯提取物。茎皮表现出对枯草芽孢杆菌的最大抑制区（10.35±0.867 mm），其次是铜绿假单胞菌（10.07±0.971 mm）。抗菌活性的结果表明，G。latissima Miq的MeOH提取物。茎皮表现出抗枯草芽孢杆菌（MIC / MBC = 625 ppm / 2500 ppm）和金黄色葡萄球菌（MIC / MBC = 2500 ppm / 5000 ppm）的活性。 G. latissima Miq。的乙酸乙酯提取物。茎皮表现出对铜绿假单胞菌（MIC / MBC = 5000 ppm / 5000 ppm）和枯草芽孢杆菌（MIC / MBC> 5000 ppm / 5000 ppm）的活性。结论：本研究的结果揭示了最有价值的信息，也支持了对G. latissima Miq的持续可持续利用。在传统的医学系统中，茎皮会变树皮。

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