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首页> 外文期刊>British Journal of Cancer >Results in Fifty Cases of Advanced Squamous Cell Carcinoma of the Head and Neck Treated by Intravenous Chemotherapy
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Results in Fifty Cases of Advanced Squamous Cell Carcinoma of the Head and Neck Treated by Intravenous Chemotherapy

机译：静脉化疗治疗头颈部晚期鳞状细胞癌50例结果

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摘要

The results of intravenous chemotherapy for advanced squamous cell carcinoma of the head and neck in 50 patients are presented. Forty patients were treated with methotrexate alone—3 patients showed partial regression of disease and a further 7 were controlled for periods of up to 4 months. Of those patients who failed to respond, or who relapsed on methotrexate, 16 were treated with combination chemotherapy. One patient showed complete regression of disease, 2 partial regression and in 2 others control was achieved for up to 4 months. A further 10 patients were treated with combination chemotherapy only, with no previous methotrexate. In this group no objective regressions were noted and only one patient was controlled for a period of 14 months. It is suggested that intravenous chemotherapy in advanced squamous cell carcinoma of the head and neck is of doubtful value.
机译：介绍了50例晚期头颈部鳞状细胞癌的静脉化疗结果。 40例患者仅接受甲氨蝶呤治疗-3例患者疾病局部消退，另外7例患者的病程长达4个月。在那些没有反应或氨甲蝶呤复发的患者中，有16人接受了联合化疗。一名患者表现出疾病的完全消退，2例部分消退，另外2例达到了长达4个月的控制。另有10例患者仅接受联合化疗，之前未使用甲氨蝶呤。在该组中，未观察到客观消退，并且仅一名患者被控制了14个月。提示在头颈部晚期鳞状细胞癌中进行静脉化疗具有可疑的价值。

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