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Effect of admission time on mortality in an intensive care unit in Mainland China: a propensity score matching analysis

机译:入院时间对中国大陆重症监护病房死亡率的影响:倾向得分匹配分析

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IntroductionThe relationship between admission time and intensive care unit (ICU) mortality is inconclusive and influenced by various factors. This study aims to estimate the effect of admission time on ICU outcomes in a tertiary teaching hospital in China by propensity score matching (PSM) and stratified analysis.MethodsA total of 2,891 consecutive patients were enrolled in this study from 1 January 2009 to 29 December 2011. Multivariate logistic regression and survival analysis were performed in this retrospective study. PSM and stratified analysis were applied for confounding factors, such as Acute Physiology and Chronic Health Evaluation II (APACHE II) score and admission types.ResultsCompared with office hour subgroup (n?=?2,716), nighttime (NT, n?=?175) subgroup had higher APACHE II scores (14 vs. 8, P?
机译:简介入院时间与重症监护病房(ICU)死亡率之间的关系尚无定论,并受多种因素影响。本研究旨在通过倾向评分匹配(PSM)和分层分析来评估入院时间对中国三级教学医院ICU结局的影响。方法从2009年1月1日至2011年12月29日,本研究共纳入2,891名连续患者在这项回顾性研究中进行了多元逻辑回归和生存分析。应用PSM和分层分析来分析混杂因素,例如急性生理和慢性健康评估II(APACHE II)得分和入院类型。结果与办公时间亚组(n?=?2,716),夜间(NT,n?=?175)进行比较)亚组的APACHE II评分较高(14 vs. 8,P 0.001),延长了在ICU的住院时间(42 vs. 24 h,P <= 0.011),医疗比例更高(8.6%vs. 3.3%,P 0.001)和紧急情况(59.4%vs. 12.2%,P 0.001)。此外,NT入院与较高的ICU死亡率[几率(OR),1.725(95%CI 1.118-2.744),P <=?0.01]和28天死亡率升高有关[14.3%vs. 3.2%;或,1.920(95%CI 1.171–3.150),P?=?0.01]。 PSM显示入院时间仍与ICU结局相关(P = 0.045)和28天的死亡风险[OR,2.187(95%CI 1.119-4.271),P = 0.022]。然而,即使周末入院与工作日入院相比与工作日入院与更高的APACHE II分数更相关,也未发现周末与工作日入院之间的死亡率差异(P?=?0.849)。结论NT入院与ICU结果差有关。这一发现可能与北领地期间缺乏现场强化医生和合格居民有关。当前的人员配置模型和培训系统应在未来得到改善。

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