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首页> 外文期刊>Infection and immunity >Bacterial hemagglutination by Neisseria gonorrhoeae.
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Bacterial hemagglutination by Neisseria gonorrhoeae.

机译：淋病奈瑟氏球菌对细菌的血凝作用。

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Direct bacterial hemagglutination was investigated with 20 clinical isolates of Neisseria gonorrhoeae. The hemagglutination tests were performed by both a macrotechnique with glass slides and a microtechnique with autotrays. Only organisms from form type 1 or 2 colonies caused hemagglutination. There was no statistical difference at a 10% or higher level in hemagglutination powers of type 1 and type 2 organisms, of male urethral and female cervical isolates, and of the eight major human blood types (ABO-Rh). Of seven erythrocyte species tested, only human cells were agglutinated. D-Mannose did not prevent the agglutination. Rabbit antigonococcal serum and high-titer antigonococcal human sera inhibited the hemagglutination. The results suggest the pili are the mediators of hemagglutination and that their specific agglutination of human erythrocytes may be a correlate of their adherence to human mucosal cells in natural infection. Also, although the procedure is presently insensitive, it is possible to detect human antigonococcal antibody by inhibition of direct bacterial hemagglutination.
机译：用20株淋病奈瑟氏菌临床分离株调查了直接细菌血凝反应。血凝试验是通过带有载玻片的宏观技术和带有自动托盘的微技术进行的。只有来自1型或2型菌落的生物才引起血凝反应。 1型和2型生物体，男性尿道和女性宫颈分离株以及八种主要人类血型（ABO-Rh）的血凝能力在10％或更高水平上均无统计学差异。在测试的七个红血球种类中，仅人类细胞被凝集。 D-甘露糖不能防止凝集。兔抗淋球菌血清和高滴度抗淋球菌人血清抑制血凝反应。结果表明菌毛是血凝的介质，并且它们对人红细胞的特异性凝集可能与其在自然感染中对人粘膜细胞的粘附有关。同样，尽管目前该方法不敏感，但可以通过抑制直接细菌血凝来检测人抗淋球菌抗体。

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