Lymphocyte activation by various Mycoplasma strains and species.

Y Naot; J G Tully; H Ginsburg

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Lymphocyte activation by various Mycoplasma strains and species.

机译：各种支原体菌株和物种激活淋巴细胞。

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The capacity of various mycoplasma strains and species to induce lymphocyte transformation in vitro was studied. Of six strains of Mycoplasma pulmonis studied, five displayed mitogenic activity with rat lymphocytes. Among those M. pulmonis strains, our MP15 isolate and the Negroni strain exhibited particularly potent mitogenic capacity. The murine mycoplasmas M. neurolyticum and M. arthritidis shared this mitogenicity for rat lymphocytes. However, the human mycoplasmas M. fermentans, M. pneumoniae, M. hominis, M. orale, and Acholeplasma laidlawii did not activate rat lymphocytes. Lymphocytes obtained from germfree rats were activated to the same extent as those from animals bred under conventional conditions. The mitogenic potency exhibited by mycoplasma was not restricted to infective microorganisms, and preparations of killed mycoplasma particles exerted an extensive lymphocyte transformation. The data show that the mitogenic activity of mycoplasmas is not confined to a single mycoplasma isolate and that it acts in a nonspecific manner.

机译：研究了各种支原体菌株和物种在体外诱导淋巴细胞转化的能力。在研究的六种肺炎支原体菌株中，五种对大鼠淋巴细胞表现出有丝分裂活性。在这些肺炎支原体菌株中，我们的MP15分离株和Negroni菌株表现出特别强的促有丝分裂能力。鼠支原体解神经支原体和关节炎支原体对大鼠淋巴细胞具有这种有丝分裂性。但是，人类支原体发酵发酵支原体，肺炎支原体，人型支原体，奥拉勒支原体和无家可食的破膜芽胞杆菌并未激活大鼠淋巴细胞。从无菌大鼠获得的淋巴细胞的活化程度与在常规条件下繁殖的动物的活化程度相同。支原体表现出的促有丝分裂能力不限于感染性微生物，并且杀死的支原体颗粒的制剂产生了广泛的淋巴细胞转化。数据表明，支原体的促有丝分裂活性不限于单个支原体分离物，并且其以非特异性方式起作用。

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《Infection and immunity》 |1977年第2期|共8页
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Y Naot; J G Tully; H Ginsburg;
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1. Mycoplasma-dependent activation of normal mouse lymphocytes: requirement for functional T lymphocytes in the cytotoxicity reaction mediated by Mycoplasma arthritidis. [J] . B C Cole, K E Aldridge, G J Sullivan, Infection and immunity . 1980,第1期

机译：正常小鼠淋巴细胞的支原体依赖性激活：由关节炎支原体介导的细胞毒性反应中功能性T淋巴细胞的需求。
2. Mycoplasma-dependent activation of normal lymphocytes: mitogenic potential of mycoplasmas for mouse lymphocytes. [J] . B C Cole, K E Aldridge, J R Ward Infection and immunity . 1977,第2期

机译：正常淋巴细胞的支原体依赖性激活：支原体对小鼠淋巴细胞的促有丝分裂潜力。
3. Mycoplasma-dependent activation of normal lymphocytes: role of arginine and nonviable mycoplasma antigen in the induction of lymphocyte-mediated cytotoxicity for syngeneic mouse target cells. [J] . K E Aldridge, B C Cole, J R Ward Infection and immunity . 1977,第2期

机译：正常淋巴细胞的支原体依赖性激活：精氨酸和无活力支原体抗原在诱导小鼠同源细胞的淋巴细胞介导的细胞毒性中的作用。
4. Phosphoproteomic Approaches to Profiling of T-lymphocytes Activated via beta-2 Integrins [C] . Erol E. Gulcicek, Christopher M. Colangelo, Kathryn L. Stone, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：通过β-2整合蛋白激活的T淋巴细胞谱分析的磷蛋白酶方法
5. The molecular biology of lymphocyte activation a study of RNA metabolism in resting and mitogen stimulated lymphocytes [D] . Mitchell, Mary F -1

机译：淋巴细胞激活的分子生物学-静息和有丝分裂原刺激的淋巴细胞中RNA代谢的研究
6. Lymphocyte activation by various Mycoplasma strains and species. [O] . Y Naot, J G Tully, H Ginsburg 1977

机译：各种支原体菌株和物种激活淋巴细胞。
7. Lymphocyte activation by various Mycoplasma strains and species [O] . Y Naot, J G Tully, H Ginsburg 1977

机译：各种支原体菌株和物种的淋巴细胞活化
8. Studies on Non-H-2-Linked Lymphocyte-Activating Determinants. II. Nonexpression of Mls Determinants in a Mouse Strain with an X-Linked B Lymphocyte Immune Defect. [R] . Ahmed, A., Scher, I. 1976

机译：非H-2连接的淋巴细胞激活决定因素的研究。 II。具有X连锁B淋巴细胞免疫缺陷的小鼠品系中mls决定因子的无表达。

Lymphocyte activation by various Mycoplasma strains and species.

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