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首页> 外文期刊>Infection and immunity >Changing agglutination activities of salivary immunoglobulin A preparations against oral streptococci.
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Changing agglutination activities of salivary immunoglobulin A preparations against oral streptococci.

机译：唾液免疫球蛋白A制剂对口腔链球菌的凝集活性变化。

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Immunoglobulin A (IgA) was prepared from samples of parotid saliva collected from two individuals over a 150-day period. Standardized solutions of the IgA were tested for agglutinating antibody activity against strains of streptococcus salivarius, S. sanguis, S. mitis, and S. mutans that had been isolated from a homologous individual on day 30 and preserved in the lyophilized state. The agglutinating activity of the standardized IgA preparations against these strains was found to change over time, whereas the agglutination patterns of IgA prepared from saliva samples collected 3 days apart were generally similar. Differences in agglutination titers were also observed between IgA samples prepared from saliva collected on day 0 and day 150. The data indicate that the oral cavity may harbor streptococci of different antigenic composition representing the same species at a given time and that parotid IgA agglutinating antibody against these serotypes changes over time.
机译：免疫球蛋白A（IgA）是在150天的时间内从两个人的腮腺唾液样本中制备的。测试了IgA的标准化溶液的抗唾液链球菌，血红链球菌，链球菌和变形链球菌菌株的凝集抗体活性，所述菌株已在第30天从同源个体中分离并保存在冻干状态。发现标准化IgA制剂对这些菌株的凝集活性随时间而变化，而从间隔3天收集的唾液样品制备的IgA的凝集模式通常相似。从第0天和第150天收集的唾液制备的IgA样品之间也观察到凝集滴度的差异。数据表明，在给定的时间，口腔可能含有代表同一物种的不同抗原组成的链球菌，而针对IgA的腮腺IgA凝集抗体这些血清型随时间变化。

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