Purification of a monocytosis-producing activity from Listeria monocytogenes.

S B Galsworthy; S M Gurofsky; R G Murray

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Purification of a monocytosis-producing activity from Listeria monocytogenes.

机译：从单核细胞增生李斯特氏菌纯化产生单核细胞增多症的活性。

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The monocytosis-producing activity (MPA) from Listeria monocytogenes is shown to be associated with the cell envelope. Both MPA and immunosuppressive activity were readily extracted with aqueous solvents and separated as two independent activities by gel filtration and ion-exchange chromatography. As little as 10 microng of the resulting MPA-containing fraction caused a ninefold elevation in the level of circulating monocytes. The molecular weight of the fraction was approximately 22,000, and it contained phosphorus and carbohydrate.

机译：单核细胞增生性李斯特菌的单核细胞增多症生产活动（MPA）与细胞包膜有关。 MPA和免疫抑制活性很容易用水性溶剂提取，并通过凝胶过滤和离子交换色谱分离为两个独立的活性。所得的含MPA的馏分中只有10毫微克导致循环单核细胞水平升高了9倍。该馏分的分子量约为22,000，并且含有磷和碳水化合物。

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《Infection and immunity》 |1977年第2期|共10页
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S B Galsworthy; S M Gurofsky; R G Murray;
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中图分类医学免疫学;
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2. Characterization and Biological Activity of the Monocytosis-producing Agent of Listeria monocytogenes [J] . Ian A. Holder, C. P. Sword Journal of bacteriology . 1969,第2期

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3. Evaluation of media for determining hemolytic activity and that of API Listeria system for identifying strains of Listeria monocytogenes. [J] . T Fujisawa, M Mori Journal of Clinical Microbiology . 1994,第4期

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6. Purification of a monocytosis-producing activity from Listeria monocytogenes. [O] . S B Galsworthy, S M Gurofsky, R G Murray 1977

机译：从单核细胞增生李斯特氏菌纯化产生单核细胞增多症的活性。
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8. FSIS Risk Assessment for Risk-Based Verification Sampling of 'Listeria monocytogenes.' [R] . 2007

机译：FsIs基于风险的验证风险评估“单核细胞增生李斯特氏菌”的取样。

Purification of a monocytosis-producing activity from Listeria monocytogenes.

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