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Effect of Bactericidal Substance from Staphylococcus aureus on Group A Streptococci II. Structural Alterations

机译:金黄色葡萄球菌的杀菌物质对A组链球菌II的影响。结构变更

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Ultrastructural alterations brought about by treatment of a β-hemolytic streptococcus with a bactericidal substance from Staphylococcus aureus are described and illustrated. The substance causes an early condensation of nucleoid deoxyribonucleic acid (DNA) and a partial loss of ribosomes. These changes are followed by a dissolution of the cell contents resulting in bacterial “ghosts” composed of empty cell wall and capsule. These morphological findings correlate with known biochemical effects of the bactericidal substance on ribonucleic acid degradation and cessation of DNA and protein synthesis.
机译:描述并举例说明了用来自金黄色葡萄球菌的杀菌物质处理β-溶血性链球菌所引起的超微结构改变。该物质引起核苷脱氧核糖核酸(DNA)的早期缩合和核糖体的部分丢失。这些变化之后,细胞内含物溶解,导致细菌“鬼魂”由空的细胞壁和胶囊组成。这些形态学发现与杀菌物质对核糖核酸降解以及DNA和蛋白质合成停止的已知生化作用相关。

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