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首页> 外文期刊>Infection and immunity >Conservation of Neisseria gonorrhoeae pilus expression regulatory genes pilA and pilB in the genus Neisseria.
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Conservation of Neisseria gonorrhoeae pilus expression regulatory genes pilA and pilB in the genus Neisseria.

机译:淋病奈瑟菌属中淋球菌菌毛表达调节基因pilA和pilB的保守性。

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The pili of Neisseria gonorrhoeae mediate bacterial adhesion to the host-susceptible tissues. We have previously reported the identification of two genes, pilA and pilB, which act in trans to regulate pilus expression. Besides this regulatory function, pilA participates in an essential function for bacterial viability. Here we show that pilA and pilB homologs are also present in a variety of other members of the Neisseriaceae family of bacteria in contrast to the gonococcal pilin gene which hybridizes only to the pathogenic Neisseria species.
机译:淋病奈瑟菌的菌毛介导细菌粘附于宿主易感组织。我们以前曾报道过鉴定两个基因pilA和pilB,它们反式调节菌毛的表达。除此调节功能外,pilA还参与了细菌生存力的基本功能。在这里,我们显示,与淋球菌菌毛蛋白基因(仅与致病性奈瑟菌球菌种杂交)相反,在菌群中其他细菌中也存在pilA和pilB同源物。

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