The signal transduction mechanism responsible for gamma interferon-induced indoleamine 2,3-dioxygenase gene expression.

Y Koide; A Yoshida

首页> 外文期刊>Infection and immunity >The signal transduction mechanism responsible for gamma interferon-induced indoleamine 2,3-dioxygenase gene expression.

【24h】

The signal transduction mechanism responsible for gamma interferon-induced indoleamine 2,3-dioxygenase gene expression.

机译：信号转导机制负责γ干扰素诱导的吲哚胺2，3-二加氧酶基因表达。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We examined the signal transduction mechanism responsible for the gamma interferon-induced indoleamine 2,3-dioxygenase (IDO) gene expression in a human monocytic cell line, THP-1. Our results suggest that gamma interferon-induced activation of protein tyrosine kinase is a prerequisite for gene expression and that activation of protein kinase C and another unknown signal(s), both of which are transduced by the protein tyrosine kinase, synergistically induce IDO gene expression. Neither Ca2+ influx nor cyclic nucleotide-dependent kinases were suggested to be involved in the signaling pathway.

机译：我们检查了信号转导机制负责人单核细胞系THP-1中的γ干扰素诱导的吲哚胺2,3-二加氧酶（IDO）基因表达。我们的结果表明，γ干扰素诱导的蛋白酪氨酸激酶激活是基因表达的前提条件，蛋白激酶C和另一个未知信号的激活均由蛋白酪氨酸激酶转导，协同诱导IDO基因表达。。提示Ca2 +内流和环状核苷酸依赖性激酶均不参与信号通路。

著录项

来源
《Infection and immunity》 |1994年第3期|共8页
作者
Y Koide; A Yoshida;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Inhibition of Indoleamine 2,3-Dioxygenase Activity by Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia trachomatis Persistence in Human Epithelial Cells [J] . Joyce A. Ibana, Robert J. Belland, Arnold H. Zea, Infection and immunity . 2011,第11期

机译：左旋-1-甲基色氨酸阻滞γ干扰素诱导的沙眼衣原体在人类上皮细胞中的持久性抑制吲哚胺2，3-二加氧酶活性。
2. Nitric Oxide-Mediated Regulation of Gamma Interferon-Induced Bacteriostasis: Inhibition and Degradation of Human Indoleamine 2,3-Dioxygenase [J] . Christian Hucke, Colin R. MacKenzie, Koku D. Z. Adjogble, Infection and immunity . 2004,第5期

机译：一氧化氮介导的γ干扰素诱导的抑菌作用的调节：人类吲哚胺2，3-双加氧酶的抑制和降解。
3. Inhibition of Chlamydia pneumoniaeReplication in Human Aortic Smooth Muscle Cells by Gamma Interferon-Induced Indoleamine 2,3-Dioxygenase Activity [J] . Laura G. Pantoja, Richard D. Miller, Julio A. Ramirez, Infection and immunity . 2000,第11期

机译：γ干扰素诱导的吲哚胺2，3-双加氧酶活性抑制人主动脉平滑肌细胞中肺炎衣原体的复制
4. Alzheimer’s disease: label-free fluorescence shows increases in indoleamine 2,3-dioxygenase (IDO) or tryptophan 2,3-dioxygenase (TDO) activity in affected areas of the brain [C] . Laura A. Sordillo, Lin Zhang, Peter P. Sordillo, Optical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis . 2019

机译：阿尔茨海默氏病：无标记的荧光显示大脑受影响区域的吲哚胺2，3-双加氧酶（IDO）或色氨酸2，3-双加氧酶（TDO）活性增加
5. Modulation of interferon-gamma receptor expression during infection with Chlamydia psittaci 6BC and its influence on indoleamine 2,3-dioxygenase. [D] . Shirey, Kari Ann. 2006

机译：感染鹦鹉热衣原体6BC期间干扰素-γ受体表达的调节及其对吲哚胺2,3-双加氧酶的影响。
6. The signal transduction mechanism responsible for gamma interferon-induced indoleamine 23-dioxygenase gene expression. [O] . Y Koide, A Yoshida 1994

机译：信号转导机制负责γ干扰素诱导的吲哚胺23-二加氧酶基因表达。
7. Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced chlamydia trachomatis persistence in human epithelial cells [O] . Ibana Joyce A, Belland Robert J, Zea Arnold H, 2011

机译：左旋-1-甲基色氨酸阻滞吲哚胺2,3-二加氧酶活性阻止γ-干扰素诱导的沙眼衣原体在人上皮细胞中的持久性

The signal transduction mechanism responsible for gamma interferon-induced indoleamine 2,3-dioxygenase gene expression.

摘要

著录项

相似文献

相关主题

期刊订阅