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首页> 外文期刊>Infection and immunity >Influence of anti-Actinobacillus actinomycetemcomitans Y4 (serotype b) lipopolysaccharide on severity of generalized early-onset periodontitis.
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Influence of anti-Actinobacillus actinomycetemcomitans Y4 (serotype b) lipopolysaccharide on severity of generalized early-onset periodontitis.

机译：抗放线放线杆菌放线杆菌Y4（血清型b）脂多糖对广泛性早发性牙周炎严重程度的影响。

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摘要

The objective of this study was to determine if a relationship exists between antibody reactive with the Actinobacillus actinomycetemcomitans serotype b lipopolysaccharide (LPS) and severity of periodontal disease in generalized early-onset periodontitis (G-EOP). The concentration of antibody reactive with A. actinomycetemcomitans serotype b LPS was determined for 102 G-EOP subjects. Analysis of the relationship between antibody reactive with A. actinomycetemcomitans serotype b LPS and measures of periodontal attachment loss indicated that the patients with the highest concentrations of antibody reactive with A. actinomycetemcomitans serotype b LPS had significantly less attachment loss. These high-responder subjects also had anti-A. actinomycetemcomitans serotype b LPS with significantly higher relative avidity. The results suggest that antibody reactive with A. actinomycetemcomitans serotype b LPS is protective in G-EOP patients.
机译：这项研究的目的是确定与广义放线型牙周炎（G-EOP）的放线杆菌放线杆菌血清b型脂多糖（LPS）反应的抗体与牙周疾病的严重性之间是否存在关系。确定了102名G-EOP受试者与放线杆菌血清型b LPS反应的抗体浓度。对与放线放线杆菌血清型b LPS反应的抗体与牙周附着力丧失之间的关系的分析表明，与放线放线杆菌血清型b LPS反应的抗体最高浓度的患者的附着力损失明显减少。这些高反应性受试者也具有抗A抗体。放线菌的血清型b LPS具有相对较高的亲和力。结果表明，与放线放线杆菌血清型b LPS反应的抗体对G-EOP患者具有保护作用。

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