Detection of Antibodies to Toxin-Coregulated Pili in Sera from Cholera Patients

Stephen R. Attridge; Gun Wallerstr?m; Firdausi Qadri; Ann-Mari Svennerholm

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Detection of Antibodies to Toxin-Coregulated Pili in Sera from Cholera Patients

机译：霍乱患者血清中毒素强化菌毛抗体的检测

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Monoclonal antibodies (MAbs) were prepared against toxin-coregulated pili (TCP) isolated from Vibrio cholerae O1 El Tor. Despite their limited bactericidal potential, two MAbs were able to mediate biotype-specific protection against experimental cholera in infant mice. These MAbs were used in immunoblotting studies to assess seroconversion to El Tor TCP following cholera. Clear anti-pilus responses were observed in five of nine patients.

机译：制备了针对霍乱弧菌 O1 El Tor毒素协同菌毛（TCP）的单克隆抗体（MAb）。尽管它们的杀菌潜力有限，但两种单克隆抗体仍能够介导针对小鼠小鼠实验性霍乱的生物型特异性保护。这些单克隆抗体在免疫印迹研究中用于评估霍乱后血清转化为El Tor TCP的血清。 9名患者中有5名观察到明显的抗菌毛反应。 展开▼

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《Infection and immunity》 |2004年第3期|共4页

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Stephen R. Attridge; Gun Wallerstr?m; Firdausi Qadri; Ann-Mari Svennerholm;
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机译：霍乱弧菌O1毒素复合菌毛在实验性霍乱和临床霍乱中的免疫原性。

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机译：霍乱患者和实验动物中霍乱肠毒素抗体的体外检测

3. The Major Subunit of the Toxin-Coregulated Pilus TcpA Induces Mucosal and Systemic Immunoglobulin A Immune Responses in Patients with Cholera Caused by Vibrio cholerae O1 and O139 [J] . Muhammad Asaduzzaman, Edward T. Ryan, Manohar John, Infection and immunity . 2004,第8期

机译：毒素致密化毛囊TcpA的主要亚基诱导霍乱弧菌O1和O139引起的霍乱患者的粘膜和全身免疫球蛋白A免疫反应

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机译：川崎病患者血清中的抗体滴度至氏菌脑膜炎菌菌菌菌毒性聚集因子（SM-HPAF）

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机译：用于在患有不孕症患者的血清中对CD52G进行抗体的抗体进行抗体的ELISA的开发

6. Detection of Antibodies to Toxin-Coregulated Pili in Sera from Cholera Patients [O] . Stephen R. Attridge, Gun Wallerström, Firdausi Qadri, 2004

机译：霍乱患者血清中毒素增强菌毛抗体的检测

7. Detection of Antibodies to Toxin-Coregulated Pili in Sera from Cholera Patients [O] . Attridge, Stephen R., Wallerström, Gun, Qadri, Firdausi, 2004

机译：霍乱患者血清中毒素增强菌毛抗体的检测

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7. 神经系统疾病患者血清中抗BP180抗体和抗BP230抗体的检测 [A] . 王亚如 . 2018

1. 用于检测患者血清中Gliadin抗体的试剂盒及其制备方法 [P] . 中国专利： CN1304042A . 2001-07-18

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3. Isolation of proteins of HTLV-III, serological detection of antibodies to HTLV-III in sera of patients with aids and pre-aids conditions, and detection of HTLV-III infection bi/immuno-assays using HTLV-III infection by immuno-assays using HTLV-III and its proteins [P] . 外国专利： IE58321B1 . 1993-09-08

机译：分离HTLV-III蛋白，血清学检测艾滋病和艾滋病患者血清中的HTLV-III抗体，以及使用HTLV-III感染通过免疫测定法检测HTLV-III感染的双向/免疫测定HTLV-III及其蛋白

4. Method for the isolation of proteins of HTLV-III, serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions and detection of HTLV-III infections by immunoassays, and a test system for use in the method [P] . 外国专利： DK165958B . 1993-02-15

机译：分离HTLV-III蛋白质的方法，对患有艾滋病和艾滋病前期状况的患者血清进行HTLV-III抗体的血清学检测以及通过免疫测定法检测HTLV-III感染的方法以及用于该方法的测试系统

5. ISOLATION OF PROTEINS OF HTLV-III,SEROLOGICAL DETECTION OF ANTIBODIES TO HTLV-III IN SERA OF PATIENTS WITH AIDS AND PRE-AIDS CONDITIONS,AND DETECTION OF HTLV-III INFECTION BY IMMUNO-ASSAYS USING HTLV-III AND ITS PROTEINS [P] . 外国专利： SG65692G . 1992-09-04

机译：艾滋病毒和艾滋病前感染者血清中HTLV-III的蛋白分离，血清对HTLV-III的血清学检测以及HTLV-III及其蛋白的免疫分析检测HTLV-III感染

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Detection of Antibodies to Toxin-Coregulated Pili in Sera from Cholera Patients

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