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Reconstruction of the Limbal Vasculature After Limbal-Conjunctival Autograft Transplantation in Pterygium Surgery: An Angiography Study

机译:翼状Con肉手术中结膜-结膜自体移植术后的肢体血管重建:血管造影研究

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Purpose.: We evaluated the angiographic features of the affected limbus in patients with pterygia and assessed limbal reconstruction outcomes after limbal-conjunctival autograft (LCA) transplantation in terms of vascular remodeling. Methods.: We studied prospectively 31 eyes of 31 patients who underwent pterygium excision and LCA transplantation; 28 eyes of 28 normal participants served as controls. Anterior segment indocyanine green angiography (ICGA) was performed for each participant preoperatively and at 1 week, and 1 and 3 months postoperatively. The perioperative angiographic features of the pterygium were compared to those in normal eyes. The structural changes of the marginal corneal vascular arcades (MCAs) and LCA were quantitatively assessed postoperatively in terms of vascular density and lacunarity. Results.: Deteriorated MCAs that extended beyond the pterygium head were observed in the pterygium group. The pterygium had a dual blood supply from the conjunctival and episcleral circulations. In terms of limbal reconstruction, the engorged reperfusion vessels arose from the adjacent episcleral vessels along the limbus at 1 week postoperatively. The reconstructed MCAs had begun to appear at 1 month postoperatively and became apparent 3 months postoperatively in 26 (83.9%) of 31 eyes of the pterygium group, resulting in a successful clinical outcome. Higher vascular density and lower lacunarity were measured in the limbus and the graft at 3 months than at 1 month (P 0.001 for all), which indicated fine reorganization of the reconstructed vessels. Conclusions.: The pterygium had a dual blood supply, and the remodeling of the affected limbus and LCA continued up to 3 months postoperatively.
机译:目的:我们评估了翼状gia肉患者患角膜缘的血管造影特征,并评估了角膜结膜自体移植(LCA)移植后的角膜缘重建结果,以评估血管重构。方法:我们对31例行翼状ery肉切除和LCA移植的患者的31只眼进行了前瞻性研究。将28名正常参与者的28只眼作为对照。术前以及术后1周,术后1和3个月对每位参与者进行前节吲哚菁绿色血管造影(ICGA)。将翼状ery肉的围手术期血管造影特征与正常眼中的进行比较。术后根据血管密度和腔隙度定量评估边缘角膜血管拱廊(MCA)和LCA的结构变化。结果:在翼状group肉组中观察到MCA恶化,超出了翼状head肉头部。翼状had肉有来自结膜和巩膜循环的双重血液供应。在角膜缘重建方面,术后1周,充盈的再灌注血管从沿角膜缘的相邻上皮巩膜血管中升起。翼状MC肉组31眼中的26眼(83.9%)在术后1个月开始出现重建的MCA,并在术后3个月变得明显。在3个月时比在1个月时,角膜缘和移植物中的血管密度更高,腔隙更低(所有P均<0.001),这表明重建后的血管组织良好。结论:翼状had肉具有双重供血,受影响的角膜缘和LCA的重塑持续至术后3个月。

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