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Report on the International Symposium on Hepatitis E, Seoul, South Korea, 2010

机译:2010年国际戊型肝炎学术研讨会报告,韩国首尔

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Hepatitis E virus (HEV), transmitted through the fecal–oral route, was first identified during waterborne epidemics of acute hepatitis in Kashmir and New Delhi, India, in 1980 (1–3). The virus was later characterized as a spherical virion of 27–34 nm in diameter with a nonenveloped, positive-sense, single-stranded RNA genome of ≈7.2 kb (4) and classified into 4 genotypes (1,2,5,6) that appear to have specific global distributions (4). Genotypes 1 and 2 are primarily responsible for HEV infections in humans; genotypes 3 and 4 can be found in animals and humans.
机译:通过粪便-口途径传播的戊型肝炎病毒(HEV),是在1980年印度克什米尔和新德里的急性肝炎的水传播流行病中首次发现的(1-3)。该病毒后来被表征为直径为27-34 nm的球形病毒体,具有约7.2 kb的无包膜,正义,单链RNA基因组(4),并分为4个基因型(1,2,5,6)似乎具有特定的全球分布(4)。基因型1和2主要负责人类HEV感染;基因型3和4可以在动物和人类中找到。

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