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首页> 外文期刊>Emerging Infectious Diseases >Severe Lower Respiratory Tract Infection in Early Infancy and Pneumonia Hospitalizations among Children, Kenya
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Severe Lower Respiratory Tract Infection in Early Infancy and Pneumonia Hospitalizations among Children, Kenya

机译：肯尼亚儿童早期婴儿期严重下呼吸道感染和肺炎住院

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Severe lower respiratory tract infection (LRTI) in infants caused by respiratory syncytial virus (RSV) has been associated with later pneumonia hospitalization among children. To determine risk for pneumonia after RSV hospitalization in infancy, we conducted a retrospective cohort analysis of 2,813 infants admitted to a hospital in Kenya and identified readmissions for pneumonia among this group during early childhood (<60 months of age). Incidence of readmission for pneumonia was higher for children whose first admission as infants was for LRTI and who were <3 months of age than for children who were first admitted as infants for non- LRTI, irrespective of RSV status. Incidence of readmission for pneumonia with wheeze was higher for children whose first admission involved RSV compared with those who had non-RSV LRTI. Excess pneumonia risk persisted for 2 years after the initial hospitalization. Close postdischarge follow-up of infants with LRTI, with or without RSV, could help prevent severe pneumonia later in childhood.
机译：由呼吸道合胞病毒（RSV）引起的婴儿严重下呼吸道感染（LRTI）与后来儿童肺炎住院有关。为了确定婴儿接受RSV住院后发生肺炎的风险，我们对肯尼亚住院的2,813名婴儿进行了回顾性队列分析，并确定了该组儿童早期（<60个月）的肺炎再入院率。与RSV状况无关，初次入院为LRTI且<3个月大的婴儿的肺炎再入院率高于初次入院为非LRTI的婴儿。与非RSV LRTI的儿童相比，首次入院涉及RSV的儿童因喘息而患肺炎的再入院率更高。初次住院后，肺炎的高危风险持续了2年。患有或不患有RSV的LRTI婴儿的出院后密切随访可以帮助预防儿童后期严重的肺炎。

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