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pVir and Bloody Diarrhea in Campylobacter jejuni Enteritis

机译:空肠弯曲菌肠炎中的pVir和血性腹泻

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The plasmid pVir may play a role in the virulence ofCampylobacter jejuni, a leading cause of bacterial gas-troenteritis. The pVir plasmid was identified in 17% of 104C. jejuni clinical isolates studied and was significantly asso-ciated with the occurrence of blood in patient stool, a mark-er of invasive infection. The pVir plasmid was notassociated with greater occurrence of diarrhea, fever, pain,vomiting, or need for patient hospitalization. Isolates con-taining pVir were also associated with the presence of atetracycline-resistance plasmid, but pVir did not transferwith tetracycline-resistance plasmids to recipient strains ofC. jejuni. The association of pVir and bloody stool suggeststhat pVir may be clinically relevant in C. jejuni infections
机译:质粒pVir可能在空肠弯曲杆菌的毒性中起作用,空肠弯曲杆菌是细菌性胃肠炎的主要原因。在104℃的17%中鉴定出pVir质粒。空肠的临床分离株已被研究,并且与患者粪便中血液的产生显着相关,后者是侵袭性感染的标志。 pVir质粒与腹泻,发烧,疼痛,呕吐或需要住院治疗的发生率较高无关。含有pVir的分离株也与四环素抗性质粒的存在有关,但pVir不能与四环素抗性质粒一起转移到C的受体菌株中。空肠。 pVir和血便的关联表明pVir在空肠弯曲杆菌感染中可能与临床相关

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