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首页> 外文期刊>Emerging Infectious Diseases >Fluoroquinolone-Resistant Group B Streptococci in Acute Exacerbation of Chronic Bronchitis
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Fluoroquinolone-Resistant Group B Streptococci in Acute Exacerbation of Chronic Bronchitis

机译：耐氟喹诺酮B组链球菌在慢性支气管炎急性发作中的作用

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To the Editor: Fluoroquinolones (FQs) that are active against strep-tococcal species (e.g., levo. oxacin and moxi. oxacin) have been recom-mended by numerous national health authorities and international organiza-tions for treating acute exacerbations of chronic bronchitis and pneumonia in adults (1). However, use of these antimicrobial drugs for treating com-munity-acquired infections has led to an increase in FQ-resistant strains in bacteria such as Streptococcus pneu-moniae. Group B streptococci (GBS, e.g., S. agalactiae) are the leading cause of invasive infections (pneumo-nia, septicemia, and meningitis) in ne-onates. GBS are also associated with bacteremia, endocarditis, and arthritis, and are responsible for deaths and ill-ness in nonpregnant women with un-derlying diseases and in elderly adults (2). We describe, to our knowledge, the fi rst GBS clinical isolate in France resistant to FQ; the isolate was from a patient treated with levo. oxacin
机译：致编辑：许多国家卫生当局和国际组织已推荐对链球菌球菌物种（例如左旋奥沙星和莫西沙星）具有活性的氟喹诺酮类药物（FQ），用于治疗慢性支气管炎和急性支气管炎的急性发作。成人肺炎（1）。但是，使用这些抗微生物药物治疗社区获得性感染已导致细菌（例如肺炎链球菌）中FQ耐药菌株的增加。 B组链球菌（GBS，例如无乳链球菌）是新生儿中侵袭性感染（肺炎，败血病和脑膜炎）的主要原因。 GBS还与菌血症，心内膜炎和关节炎相关，并且是患有各种疾病的非孕妇和老年人的死亡和疾病的原因（2）。据我们所知，我们描述了法国首个对FQ有抗药性的GBS临床分离株。分离株来自于左旋病毒治疗的患者。奥沙星

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