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首页> 外文期刊>Emerging Infectious Diseases >Usefulness of Seminested Polymerase Chain Reaction for Screening Blood Donors at Risk for Malaria in Spain
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Usefulness of Seminested Polymerase Chain Reaction for Screening Blood Donors at Risk for Malaria in Spain

机译：半巢式聚合酶链反应在西班牙筛查有疟疾风险的献血者中的有用性

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To the Editor: Assurance of blood safety relies on effective public health surveillance for infectious diseases. Appropriate management of emerging disease threats requires that this surveillance be combined with screening measures to eliminate or minimize the risk of transmitting transfusion- associated disease. Diseases with a long and relatively asymptomatic period (malaria) during which microorganisms are present in the blood are of particular concern for transfusion safety. Many reports have shown that falciparum malaria can remain in the bloodstream for a long time (even years) as an asymptomatic infection (1). Parasitic contamination of donated blood can occur only if the donor has parasitemia, usually asymptomatic, at the time the blood is collected. In accordance with legislation of the European Community and the United States, travelers who have visited malaria-endemic areas may be accepted as regular blood donors 6 months after return to the nonendemic area, providing they have been free of unexplained febrile illnesses and have not taken antimalarial drugs (2,3). Immigrants or visitors from endemic areas may donate blood 3 years after they leave the area if they have been asymptomatic in the interim. Donations to be used for the preparation of plasma, plasma components, or derivatives devoid of intact erythrocytes are exempt from these restrictions.
机译：致编辑：血液安全的保证依赖于对传染病的有效公共健康监测。对新出现的疾病威胁进行适当的管理，要求将这种监测与筛查措施相结合，以消除或最小化传播与输血有关的疾病的风险。血液中存在微生物的较长且相对无症状的疾病（疟疾）对于输血安全性特别重要。许多报告表明，恶性疟疾可以作为无症状感染在血液中保留很长一段时间（甚至数年）（1）。仅当捐献者在采血时患有寄生虫病（通常无症状）时，才会发生捐献血液的寄生虫污染。根据欧洲共同体和美国的法律，访问过疟疾流行地区的旅行者可在返回非流行地区六个月后被接受为常规献血者，条件是他们没有无法解释的发热性疾病且未服用抗疟药（2,3）。如果在此期间无症状，来自流行地区的移民或游客在离开该地区三年后可以献血。用于制备血浆，血浆成分或不含完整红细胞的衍生物的捐赠不受这些限制。

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