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首页> 外文期刊>Emerging Infectious Diseases >Verona Integron–encoded Metallo-β-Lactamase 1 in Enterobacteria, Ontario, Canada
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Verona Integron–encoded Metallo-β-Lactamase 1 in Enterobacteria, Ontario, Canada

机译：Verona Integron编码的Enterobacteria，加拿大安大略省的Metallo-β-内酰胺酶1

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To the Editor: Among Enterobacteriaceae, Verona integron–encoded metallo-β-lactamase 1 (VIM- 1) has been found only in Klebsiella pneumoniae in North America (1). We report 4 VIM-1–producing Enterobacteriaceae isolated from 4 patients at 3 hospitals in Ontario, Canada. Patient 1, a 61-year-old man, was initially hospitalized in Italy for presumed pneumonia and was treated with levofloxacin during his 6-month stay in Italy. Upon returning to Ontario, Canada, he was admitted to hospital 1 in August 2010 because of diabetic ketoacidosis and began empiric treatment with metronidazole and gentamicin. Urine cultures were positive for a carbapenem-resistant Escherichia coli (strain GN531). Two days later, the patient had a fever and a blood culture was positive for E. coli (strain GN532), which was also resistant to carbapenems. During his hospitalization, the patient was isolated and received droplet precaution because of his travel history until he was discharged home.
机译：致编者：在肠杆菌科中，仅在北美肺炎克雷伯菌中发现了维罗纳整合子编码的金属β-内酰胺酶1（VIM-1）。我们报告了从加拿大安大略省3所医院的4名患者中分离出4株产生VIM-1的肠杆菌科。患者1，一名61岁的男性，最初因推测的肺炎在意大利住院，并在其6个月的意大利住宿期间接受了左氧氟沙星治疗。回到加拿大安大略省后，由于糖尿病性酮症酸中毒，他于2010年8月入一医院，并开始用甲硝唑和庆大霉素进行经验治疗。尿培养物中对碳青霉烯类耐药的大肠杆菌（菌株GN531）呈阳性。两天后，患者发烧，血液培养对大肠杆菌（菌株GN532）呈阳性，而大肠杆菌对碳青霉烯类也有抵抗力。在他住院期间，由于他的旅行历史直到他出院回家，该病人被隔离并接受了飞沫预防。

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