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Effectiveness of Pneumococcal Polysaccharide Vaccine for Preschool-Age Children with Chronic Disease

机译:肺炎球菌多糖疫苗对学龄前儿童慢性病的有效性

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To estimate the effectiveness of pneumococcal polysaccharide vaccine, we serotyped isolates submitted to the Pneumococcal Sentinel Surveillance System from 1984 to 1996 from 48 vaccinated and 125 unvaccinated children 2 to 5 years of age. Effectiveness against invasive disease caused by serotypes included in the vaccine was 63%. Effectiveness against serotypes in the polysaccharide vaccine but not in a proposed seven-valent protein conjugate vaccine was 94%.
机译:为了评估肺炎球菌多糖疫苗的有效性,我们对1984年至1996年间提交给肺炎球菌前哨监视系统的48例接种疫苗和125例2至5岁的未接种疫苗的儿童进行了血清分型。疫苗中包括的血清型引起的侵袭性疾病的有效率为63%。在多糖疫苗中对血清型的有效率为94%,而在拟议的七价蛋白偶联疫苗中则没有。

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