DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae.

C N Giroux; J R Mis; M K Pierce; S E Kohalmi; B A Kunz

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DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae.

机译：酿酒酵母（Saccharomyces cerevisiae）SUP4-o基因自发突变的DNA序列分析。

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A collection of 196 spontaneous mutations in the SUP4-o gene of the yeast Saccharomyces cerevisiae was analyzed by DNA sequencing. The classes of mutation identified included all possible types of base-pair substitution, deletions of various lengths, complex alterations involving multiple changes, and insertions of transposable elements. Our findings demonstrate that at least several different mechanisms are responsible for spontaneous mutagenesis in S. cerevisiae.

机译：通过DNA测序分析了酵母Saccharomyces cerevisiae的SUP4-o基因中的196个自发突变。鉴定出的突变类型包括所有可能的碱基对取代，各种长度的缺失，涉及多种变化的复杂改变以及可转座因子的插入。我们的发现表明，至少有几种不同的机制可导致酿酒酵母中的自发诱变。

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《Molecular and Cellular Biology》 |1988年第2期|共4页
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C N Giroux; J R Mis; M K Pierce; S E Kohalmi; B A Kunz;
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中图分类细胞生物学;
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1. Disruption of the RAD52 gene alters the spectrum of spontaneous SUP4-o mutations in Saccharomyces cerevisiae. [J] . B A Kunz, J D Armstrong, K Badiani, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1989,第3期

机译：RAD52基因的破坏改变了酿酒酵母中自发的SUP4-o突变的光谱。
2. DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. [J] . Harfe BD, Jinks-Robertson S Molecular cell . 2000,第6期

机译：当绕过酿酒酵母中的自发性DNA损伤时，DNA聚合酶zeta会引入多个突变。
3. Mutational analysis of Rox1, a DNA-bending repressor of hypoxic genes in Saccharomyces cerevisiae. [J] . J Deckert, A M Rodriguez Torres, J T Simon, Molecular and Cellular Biology . 1995,第11期

机译：Rox1突变分析，酿酒酵母中的低氧基因可弯曲的DNA阻遏物。
4. Tissue culture-induced mutations and overexpression of full-length cDNAs as a tool for functional analysis of rice genes [C] . H. Hirochika, A. Miyao, M. Yamazaki, International Rice Genetics Symposium . 2007

机译：组织培养诱导的全长CDNA的突变和过度表达作为水稻基因功能分析的工具
5. C-terminal flap endonuclease (rad27) mutations: Lethal interactions with a DNA ligase I mutation (cdc9-p) and suppression by proliferating cell nuclear antigen (POL30) in Saccharomyces cerevisiae. [D] . Karanja, Kenneth Kimani. 2009

机译：C末端皮瓣内切核酸酶（rad27）突变：与酿酒酵母中DNA连接酶I突变（cdc9-p）的致命相互作用以及通过增殖细胞核抗原（POL30）的抑制作用。
6. DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae. [O] . C N Giroux, J R Mis, M K Pierce, 1988

机译：酿酒酵母（Saccharomyces cerevisiae）SUP4-o基因自发突变的DNA序列分析。
7. DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae. [O] . Giroux, C N, Mis, J R, Pierce, M K, 1988

机译：酿酒酵母（Saccharomyces cerevisiae）SUP4-o基因自发突变的DNA序列分析。

DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae.

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