Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

S Subramani; R Mulligan; P Berg

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Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

机译：小鼠二氢叶酸还原酶互补脱氧核糖核酸在猿猴病毒40载体中的表达。

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A mouse complementary deoxyribonucleic acid segment coding for the enzyme dihydrofolate reductase has been cloned in two general classes of vectors containing simian virus 40 deoxyribonucleic acid: (i) those that can be propagated as virions in permissive cells and (ii) those that can be introduced into and maintained stably in various mammalian cells. Both types of vectors express the mouse dihydrofolate reductase by using signals supplied by simian virus 40 deoxyribonucleic acid sequences. Moreover, plasmid vectors carrying the complementary deoxyribonucleic acid segment can complement Chinese hamster ovary cells lacking dihydrofolate reductase.

机译：已将编码二氢叶酸还原酶的小鼠互补脱氧核糖核酸片段克隆到包含猿猴病毒40脱氧核糖核酸的两大类普通载体中：（i）可以作为病毒体在允许的细胞中繁殖的载体，和（ii）可以引入的载体进入并稳定地维持在各种哺乳动物细胞中。两种类型的载体均通过使用猿猴病毒40个脱氧核糖核酸序列提供的信号来表达小鼠二氢叶酸还原酶。此外，带有互补的脱氧核糖核酸片段的质粒载体可以补充缺乏二氢叶酸还原酶的中国仓鼠卵巢细胞。

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《Molecular and Cellular Biology》 |1981年第9期|共11页
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S Subramani; R Mulligan; P Berg;
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中图分类细胞生物学;
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1. Identification of the Simian Virus 40 Which Replicates When Simian Virus 40-Transformed Human Cells Are Fused with Simian Virus 40-Transformed Mouse Cells or Superinfected with Simian Virus 40 Deoxyribonucleic Acid [J] . Saul Kit, T. Kurimura, McKay Brown, Journal of Virology . 1970,第1期

机译：鉴定Simian病毒40，当Simian病毒40转化的人体细胞与Simian病毒40转化的小鼠细胞融合或用Simian病毒40脱氧核糖核酸进行超育
2. Identification of the Simian Virus 40 Which Replicates When Simian Virus 40-Transformed Human Cells Are Fused with Simian Virus 40-Transformed Mouse Cells or Superinfected with Simian Virus 40 Deoxyribonucleic Acid [J] . Saul Kit, T. Kurimura, McKay Brown, Journal of Virology . 1970,第1期

机译：鉴定Simian病毒40，当Simian病毒40转化的人体细胞与Simian病毒40转化的小鼠细胞融合或用Simian病毒40脱氧核糖核酸进行超育
3. Identification of the Simian Virus 40 Which Replicates When Simian Virus 40-Transformed Human Cells Are Fused with Simian Virus 40-Transformed Mouse Cells or Superinfected with Simian Virus 40 Deoxyribonucleic Acid [J] . Saul Kit, T. Kurimura, McKay Brown, Journal of Virology . 1970,第1期

机译：鉴定Simian病毒40，当Simian病毒40转化的人体细胞与Simian病毒40转化的小鼠细胞融合或用Simian病毒40脱氧核糖核酸进行超育
4. Computational Analysis of Nucleosome Positioning Signals in the Simian Virus 40 Chromatin [C] . Hongyan Zhao, Hong Yan International MultiConference of Engineers and Computer Scientists . 2009

机译：亚麻病毒40染色质中核心定位信号的计算分析
5. Fluorescent markers for computer modeled antisense peptide nucleic acids against Simian virus 40 large T-antigen. [D] . Doss, Alan. 2000

机译：计算机模拟的针对猿猴病毒40大T抗原的反义肽核酸的荧光标记。
6. Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. [O] . S Subramani, R Mulligan, P Berg 1981

机译：小鼠二氢叶酸还原酶互补脱氧核糖核酸在猿猴病毒40载体中的表达。
7. Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. [O] . Subramani, S, Mulligan, R, Berg, P 1981

机译：小鼠二氢叶酸还原酶互补脱氧核糖核酸在猿猴病毒40载体中的表达。

Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

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