A 5'-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells.

A Klarsfeld; P Daubas; B Bourachot; J P Changeux

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A 5'-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells.

机译：鸡乙酰胆碱受体α-亚基基因的5'侧翼区域赋予组织特异性和转染细胞中表达的发育控制。

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The 5' end and promoter region of the alpha-subunit gene of chicken muscle acetylcholine receptor was mapped and sequenced. It includes a TATA and a CAAT box and a potential Sp1-binding site. When inserted in front of the chloramphenicol acetyltransferase gene, this promoter (including 850 base pairs of upstream sequence) directed high transient chloramphenicol acetyltransferase expression in transfected mouse C2.7 myotubes but not in C2.7 myoblasts or nonmyogenic 3T6 cells.

机译：绘制并测序了鸡肌肉乙酰胆碱受体α-亚基基因的5'末端和启动子区域。它包括一个TATA和一个CAAT盒以及一个潜在的Sp1结合位点。当插入氯霉素乙酰基转移酶基因的前面时，此启动子（包括850个碱基对的上游序列）指导转染的小鼠C2.7肌管中瞬时氯霉素乙酰基转移酶的高表达，但在C2.7成肌细胞或非肌源性3T6细胞中却没有。

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《Molecular and Cellular Biology》 |1987年第2期|共5页
作者
A Klarsfeld; P Daubas; B Bourachot; J P Changeux;
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中图分类细胞生物学;
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1. Multiple elements in the distal part of the 1.2 kb 5'-flanking region of the rat GnRH receptor gene regulate gonadotrope-specific expression conferred by proximal domain. [J] . Pincas H, Forrai Z, Chauvin S, Molecular and Cellular Endocrinology . 1998,第1a2期

机译：大鼠GnRH受体基因1.2 kb 5'侧翼区域远端的多个元件调节近端域赋予的促性腺激素特异性表达。
2. Isolation and characterization of the mouse acetylcholine receptor delta subunit gene: identification of a 148-bp cis-acting region that confers myotube-specific expression. [J] . T J Baldwin, S J Burden Journal of cell biology . 1988,第6期

机译：小鼠乙酰胆碱受体δ亚基基因的分离和鉴定：鉴定赋予肌管特异性表达的148bp顺式作用区。
3. Subtype-specific regulation of the expression and function of muscarinic acetylcholine receptors in embryonic chicken retinal cells. [J] . Goin JC, Nathanson NM Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2002,第4期

机译：亚型特异性调节胚胎鸡视网膜细胞中毒蕈碱型乙酰胆碱受体的表达和功能。
4. Nicotinic acetylcholine receptor functions in the CNS investigated with a novel method of stereotaxic gene re-expression in knockout mice [C] . Uwe Maskos, Sylvie Granon, Philippe Faure, Symposium on Understanding Nicotine and Tobacco Addiction . 2006

机译：在CNS中的烟碱乙酰胆碱受体功能以敲除小鼠的一种新方法研究了一种新的立体基因的方法
5. Analysis of the 5' cis-regulatory region of the seed storage protein gene helianthinin: A promoter proximal region confers regionalized seed-specific expression [D] . Nunberg, Andrew Neil 1995

机译：种子贮藏蛋白基因helinthinin 5'顺式调节区的分析：一个启动子近端区域赋予区域化的种子特异性表达
6. A 5-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells. [O] . A Klarsfeld, P Daubas, B Bourachot, 1987

机译：鸡乙酰胆碱受体α-亚基基因的5侧翼区域赋予组织特异性和转染细胞中表达的发育控制。
7. A 5'-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells. [O] . Klarsfeld, A, Daubas, P, Bourachot, B, 1987

机译：鸡乙酰胆碱受体α-亚基基因的5'侧翼区域赋予组织特异性和转染细胞中表达的发育控制。

A 5'-flanking region of the chicken acetylcholine receptor alpha-subunit gene confers tissue specificity and developmental control of expression in transfected cells.

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