• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >The remineralization effectiveness of PAMAM dendrimer with different terminal groups on demineralized dentin in vitro
【24h】

The remineralization effectiveness of PAMAM dendrimer with different terminal groups on demineralized dentin in vitro

机译：不同末端基团的PAMAM树状大分子在矿物质上的再矿化作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of this study was to examine the dentin remineralization extent that poly(amido amine) (PAMAM) induces quantitatively, and select the most effective kind of PAMAM with a certain terminal group for dentin remineralization, both for the first time. Prepared demineralized dentin specimens were divided into four groups: (1) dentin coated with deionized water, (2) dentin coated with PAMAM-OH, (3) dentin coated with PAMAM-COOH, and (4) dentin coated with PAMAM-NH2. Specimens were then treated with artificial saliva at 37 °C for 28 days. The remineralized dentin specimens were examined by transverse microradiography (TMR), hardness testing, scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). The SEM images were also analyzed with Image-Pro Plus software. The three treatment groups all induced lower mineral loss, lower lesion depth, higher dentin hardness, higher blocking rate of dentin tubules and higher percentages of Ca and P elements than the control group. PAMAM-NH2 or PAMAM-COOH induced lower mineral loss, lower lesion depth and a higher blocking rate of dentin tubules than PAMAM-OH. There was no significant difference between PAMAM-NH2 and PAMAM-COOH with regard to mineral loss, lesion depth, dentin hardness, blocking rate of dentin tubules and percentages of Ca and P elements. In conclusion, PAMAM with different terminal groups could induce dentin remineralization, and PAMAM-NH2 or PAMAM-COOH showed the strongest remineralization capabilities on demineralized dentin.
机译：这项研究的目的是定量检查聚氨基酰胺（PAMAM）诱导的牙本质再矿化程度，并首次选择具有一定末端基团的最有效的PAMAM类型进行牙本质再矿化。制备的脱矿质牙本质样品分为四组：（1）去离子水包被的牙本质，（2）涂有PAMAM-OH的牙本质，（3）涂有PAMAM-COOH的牙本质，和（4）涂有PAMAM-NH < small> 2 。然后将标本在37°C下用人工唾液处理28天。再矿化的牙本质样品通过横向显微射线照相术（TMR），硬度测试，扫描电子显微镜（SEM）和能量分散光谱（EDS）进行检查。 SEM图像也用Image-Pro Plus软件分析。这三个治疗组均比对照组引起更低的矿物质损失，更低的病变深度，更高的牙本质硬度，更高的牙本质小管阻塞率以及更高的钙和磷元素百分比。与PAMAM-OH相比，PAMAM-NH 2 或PAMAM-COOH引起的矿物质损失减少，病灶深度减小和牙本质小管阻塞率更高。 PAMAM-NH 2 与PAMAM-COOH在矿物质流失，病变深度，牙本质硬度，牙本质小管阻塞率以及钙和钙的百分比方面无显着差异。 P元素。总之，具有不同末端基团的PAMAM可以诱导牙本质再矿化，而PAMAM-NH 2 或PAMAM-COOH在去矿质的牙本质上具有最强的再矿化能力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号