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首页> 外文期刊>Journal of Clinical Microbiology >Human disease in Europe caused by a granulocytic Ehrlichia species.
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Human disease in Europe caused by a granulocytic Ehrlichia species.

机译：欧洲的人类疾病是由粒状埃希氏菌引起的。

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Human granulocytic ehrlichiosis (HGE) was recently described in North America. It is caused by an Ehrlichia species closely related to Ehrlichia phagocytophila and Ehrlichia equi, recognized to infect mostly ruminants and horses, respectively. The vector in North America is the tick Ixodes scapularis, which is also the vector of the Lyme disease agent, Borrelia burgdorferi. Previous serologic studies in patients with a diagnosis of Lyme borreliosis indicate that HGE may exist in Europe. We report the first documented case of HGE in Europe. The diagnosis was established by seroconversion to E. equi and the HGE agent and by PCR with sequence analysis of the gene encoding the HGE agent 16S rRNA. Interestingly, the patient presented with a self-limited but moderately severe illness. Thus, European physicians need to be aware that HGE exists in Europe and that the diagnosis should be considered in febrile patients with tick bites in areas where Lyme disease is endemic.
机译：北美最近描述了人类粒细胞埃希氏菌病（HGE）。它是由与吞噬性埃里希氏菌和马眼埃里希氏菌密切相关的埃里希氏菌引起的，分别被认为主要感染反刍动物和马。北美的媒介是the虱（Ixodes scapularis），它也是莱姆病病原体伯氏疏螺旋体（Borrelia burgdorferi）的媒介。先前对诊断为莱姆病的患者进行了血清学检查，结果表明欧洲可能存在HGE。我们报告了欧洲首例有记录的HGE病例。通过血清转化为马大肠杆菌和HGE试剂并通过PCR和编码HGE试剂16S rRNA的基因的序列分析来建立诊断。有趣的是，患者出现了自我限制但中等程度的严重疾病。因此，欧洲医师需要意识到在欧洲存在HGE，并且应在莱姆病流行地区的有tick咬的高热患者中考虑诊断。

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