...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Microbiology >Analysis of Genetic Diversity of Streptococcus suis Clinical Isolates from Pigs in Spain by Pulsed-Field Gel Electrophoresis
【24h】

Analysis of Genetic Diversity of Streptococcus suis Clinical Isolates from Pigs in Spain by Pulsed-Field Gel Electrophoresis

机译：猪场猪链球菌临床分离株遗传多样性的脉冲场凝胶电泳分析

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Pulsed-field gel electrophoresis (PFGE) was used to investigate the diversity of Streptococcus suis isolates of various serotypes recovered from swine clinical samples in Spain. Capsular types 9 (64.9%) and 2 (14.8%) were the most frequently isolated serotypes followed by serotype 7 (5.9%) and serotype 8 (4.3%). The PFGE results of this study with 60 different pulsotypes indicate a great genetic diversity among the S. suis isolates, which is consistent with the broad distribution of S. suis in the swine population. Forty-five percent of the pulsotypes corresponded to single isolates, no pulsotype was common to all farms, and at least 3 different pulsotypes were isolated in 56% of herds in which more than 3 clinical isolates were analyzed. These results reveal a great diversity both between and within herds throughout the strains of S. suis studied, demonstrating that different strains of S. suis are associated with infection in pigs. Some pulsotypes were more frequently isolated and exhibited a wider distribution over herds than others, and were the unique or predominant strains in several herds, suggesting the existence of a prevalent or a few prevalent clones responsible for a large proportion of clinical cases. Overall, the great genetic heterogeneity of the clinical strains of S. suis, the isolation of different strains within the same herd, and the predominance of particular strains in some herds are evidence that infection by S. suis is a dynamic process and reinforce the idea that the epidemiology of S. suis infection is very complex.
机译：脉冲场凝胶电泳（PFGE）用于研究从西班牙猪临床样本中回收的各种血清型的猪链球菌分离株的多样性。荚膜类型9（64.9％）和2（14.8％）是最常见的血清型，其次是血清型7（5.9％）和血清型8（4.3％）。这项具有60种不同脉冲类型的研究的PFGE结果表明， S之间具有很大的遗传多样性。 suis 分离株，与 S的广泛分布相一致。猪群中的猪。 45％的脉冲型对应于单个分离株，所有养殖场均没有相同的脉冲型，并且在56％的畜群中分离出了至少3种不同的脉冲型，其中对3种以上的临床分离株进行了分析。这些结果表明，在整个 S菌株中，牛群之间和牛群内部都有很大的差异。 suis 进行了研究，证明了不同的 S菌株。猪与猪感染有关。一些脉冲型比其他脉冲型更频繁地被分离并且在畜群中表现出更广泛的分布，并且是几种畜群中唯一或占主导地位的菌株，这表明存在大量临床病例的流行克隆或少数流行克隆。总体而言， S临床菌株具有巨大的遗传异质性。 suis ，同一猪群中不同菌株的隔离以及某些猪群中特定菌株的优势，都证明了 S的感染。 suis 是一个动态过程，强化了 S流行病学这一观念。猪的感染非常复杂。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号