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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Thyroid Function In Type 2 Diabetes Mellitus and in Diabetic Nephropathy
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Thyroid Function In Type 2 Diabetes Mellitus and in Diabetic Nephropathy

机译：2型糖尿病和糖尿病性肾病的甲状腺功能

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Introduction: Diabetic patients have higher prevalence of thyroid disorders than the general population which may have an influence on diabetic management. The present study compared the levels of thyroid hormones, serum creatinine, glycated haemoglobin and urine microalbumin between type 2 diabetics without any complications, type 2 diabetics with nephropathy and age and sex matched normal controls.Result: The mean serum T3 level in type 2 diabetics without any complications was 91.27 ± 14.56 ng/dl, in type 2 diabetics with nephropathy was 88.5320 ± 30.87 ng/dl and in controls was 134.98 ± 28.55 ng/dl. The mean serum T4 level in type 2 diabetics without any complications was 7.73 ± 1.42 μg/dl, in type 2 diabetics with nephropathy was 7.25 ± 2.72 μg/dl and in controls was 8.61 ± 1.73 μg/dl. The mean serum TSH level in type 2 diabetics without any complications was 3.99 ± 1.87 μIU/ml, in type 2 diabetics with nephropathy was 4.27 ± 1.62 μIU/ml and in controls was 2.07 ± 1.09 μIU/ml. Correlations between T3, T4, TSH with serum creatinine, glycated haemoglobin were not statistically significant in type 2 diabetes without any complications and diabetic nephropathy. We found a statistically significant correlation between T3 and urine microalbumin in patients with diabetic nephropathy.Conclusion: Failure to recognize the presence of abnormal thyroid hormone levels may be a primary cause of poor management of diabetes mellitus type 2. Therefore there is a need for the routine assay of thyroid hormones in type 2 diabetics and diabetic nephropathy in order to improve the quality of life and reduce the morbidity.
机译：简介：糖尿病患者的甲状腺疾病患病率高于一般人群，这可能对糖尿病管理产生影响。本研究比较了2型糖尿病患者（无并发症），2型糖尿病合并肾病以及年龄和性别与正常对照者之间甲状腺激素，血清肌酐，糖化血红蛋白和尿微量白蛋白的水平。结果：2型糖尿病患者的平均血清T3水平没有任何并发​​症的是91.27±14.56 ng / dl，患有肾病的2型糖尿病患者是88.5320±30.87 ng / dl，对照组是134.98±28.55 ng / dl。没有任何并发​​症的2型糖尿病患者的平均血清T4水平为7.73±1.42μg/ dl，患有肾病的2型糖尿病患者的平均血清T4水平为7.25±2.72μg/ dl，而对照组为8.61±1.73μg/ dl。没有任何并发​​症的2型糖尿病患者的平均血清TSH水平为3.99±1.87μIU/ ml，患有肾病的2型糖尿病患者的平均血清TSH水平为4.27±1.62μIU/ ml，对照组为2.07±1.09μIU/ ml。在没有任何并发​​症和糖尿病性肾病的2型糖尿病中，T3，T4，TSH与血清肌酐，糖化血红蛋白之间的相关性无统计学意义。我们发现糖尿病性肾病患者的T3与尿微量白蛋白之间存在统计学上的显着相关性。结论：无法认识到异常甲状腺激素水平的存在可能是2型糖尿病管理不善的主要原因。因此，需要常规测定2型糖尿病和糖尿病肾病患者甲状腺激素的水平，以改善生活质量并降低发病率。

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