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Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?

机译:催产后疱疹:胎盘是免疫反应的唯一靶点吗?

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Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period.
机译:妊娠疱疹(HG)是一种自身免疫性疾病,很少使妊娠复杂化。它的发病机理尚未阐明,因为它来自免疫,遗传和激素因素之间的复杂相互作用。我们介绍了一位代孕妈妈发生的HG病例,该代孕妈妈通过捐卵和体外受精(IVF)实现了妊娠。该病在妊娠26周零6天时出现,尽管口服和局部使用皮质类固醇激素,但随后恶化。通过选择性剖宫产在妊娠35周和2天时分娩出健康的婴儿,其临床表现在产后期得到解决。

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