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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Cytopathological Pattern of Tubercular Lymphadenopathy on FNAC: Analysis of 550 Consecutive Cases
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Cytopathological Pattern of Tubercular Lymphadenopathy on FNAC: Analysis of 550 Consecutive Cases

机译：FNAC的结核性淋巴结病的细胞病理学模式：550例连续病例分析

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Background: Fine needle aspiration cytology (FNAC) of lymph nodes is a simple, cost effective, out-patient procedure used for diagnosis of various causes of lymphadenopathies. In tuberculous lymphadenitis, it not only used for the cytological diagnosis but also used for other ancillary testing such as Ziehl- Neelsen staining and AFB Culture.Aims: Our study was designed to evaluate the cytopathological pattern of FNAC aspirate of patients presenting with lymphadenopathy with special reference to tuberculous lymphadenopathy.Materials and Methods: In this study all the patients referred to the cytopathology lab for FNAC of lymph nodes between January 2011 to June, 2013 were included. Out of 1050 patients presenting with lymphadenopathies, there were 550 cases of tuberculous lymphadenitis. The cytopathological findings of these 550 cases were analyzed.Results: A female preponderance was noted in our study with maximum incidence in the 3rd decade. Cervical lymph nodes were the most common nodes to be involved. Gross examination of aspirate showed maximum cases (74.5.2%) of whitish material. Among the four cytological patterns on FNAC, maximum cases demonstrated caseous necrotic material with degenerated inflammatory cells. Ziehl- Neelsen staining showed overall AFB positivity of 44.54%. Maximum AFB positivity was seen in cases having caseous necrosis only.Conclusion: FNAC is a simple, cost effective technique with high degree of accuracy in diagnosing Tubercular Lymphadenitis. Despite certain limitations and pitfalls, FNAC coupled with Ziehl- Neelson staining should be the 1st line investigation in cases with lymphadenopaty, in a developing country with high prevalence rate of tuberculosis.
机译：背景：淋巴结细针穿刺细胞学检查（FNAC）是一种简单，经济高效的门诊程序，用于诊断各种原因的淋巴腺病。在结核性淋巴结炎中，它不仅用于细胞学诊断，还用于诸如Ziehl-Neelsen染色和AFB培养之类的其他辅助检查。目的：本研究旨在评估患有特殊淋巴结病的FNAC抽吸物的细胞病理学模式材料与方法：本研究纳入2011年1月至2013年6月间所有转诊至细胞病理实验室的淋巴结FNAC患者。在1050名淋巴腺病患者中，有550例结核性淋巴结炎。结果：在我们的研究中发现女性占优势，在第三个十年中发病率最高。颈淋巴结是最常见的淋巴结。抽吸物的大体检查显示发白的物质最多（74.5.2％）。在FNAC的四种细胞学模式中，最大病例显示出干酪样坏死物质，并伴有变性的炎症细胞。 Ziehl-Neelsen染色显示总AFB阳性率为44.54％。结论：FNAC是一种简单，经济高效的技术，在诊断结核性淋巴结炎时具有很高的准确度。尽管存在一定的局限性和缺陷，但在结核病高发的发展中国家，FNAC联合Ziehl-Neelson染色应作为淋巴腺瘤病例的一线研究。

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