...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Unusually Aggressive Primary Testicular Diffuse Large B Cell Lymphoma with Post Therapy Extensive Metastasis
【24h】

Unusually Aggressive Primary Testicular Diffuse Large B Cell Lymphoma with Post Therapy Extensive Metastasis

机译：异常侵袭性原发性睾丸弥漫性大B细胞淋巴瘤治疗后广泛转移

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Primary Testicular Lymphoma (PTL) is a rare intermediate to high grade tumour, diffuse large cell being the most common type. Unlike nodal Diffuse Large B-Cell Lymphoma (DLBCL), testicular DLBCL has a less aggressive course and better prognosis. Metastasis is uncommon in testicular DLBCL. Commonly involved sites are contralateral testes, Waldeyers ring, skin, lung, Central Nervous System (CNS) and prostate, however the kidneys, liver, bone marrow, pleura and bones are more rarely involved. We report a case of testicular DLBCL which has metastasized to skin and bone marrow with an aggressive clinical course in a year, in-spite of combined modality of therapy given to the patient. Bone marrow infiltration is common and well documented with nodal DLBCL, however there is no published literature for simultaneous bone marrow and skin infiltration in testicular DLBCL till date. Other large studies done in the west have shown that distinct metastasis is usually common but the median progression-free survival is usually in years. This case stresses on shorter period of progression after standard treatment protocol in this part of the world, thus highlighting the need for other extensive studies to define specific treatment protocol for testicular DLBCL.
机译：原发性睾丸淋巴瘤（PTL）是高级别肿瘤的罕见中间产物，弥漫性大细胞是最常见的类型。与淋巴结弥漫性大B细胞淋巴瘤（DLBCL）不同，睾丸DLBCL的侵袭性较小，预后较好。睾丸DLBCL中转移很少见。通常涉及的部位是对侧睾丸，瓦尔德环，皮肤，肺，中枢神经系统（CNS）和前列腺，但是肾脏，肝脏，骨髓，胸膜和骨骼很少受累。我们报告了一例睾丸DLBCL，尽管给予患者联合治疗的方式，但在一年内它已转移至皮肤和骨髓，并具有侵略性临床病程。淋巴结浸润是常见的骨髓浸润性淋巴结结节病，并有文献报道，但是迄今为止，尚无公开文献报道睾丸DLBCL同时发生骨髓和皮肤浸润。在西方进行的其他大型研究表明，转移灶通常很常见，但无进展生存期的中位数通常是数年。该病例强调在世界这部分地区接受标准治疗方案后，病程会缩短，因此强调了需要进行其他广泛研究以定义睾丸DLBCL的具体治疗方案。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号