...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Can Vitamin B-Complex Aggravate the Carbamazepine Induced ToxicEpidermal Necrolysis?
【24h】

Can Vitamin B-Complex Aggravate the Carbamazepine Induced ToxicEpidermal Necrolysis?

机译：维生素B复合物会加剧卡马西平所致的中毒表皮坏死溶解吗？

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Toxic Epidermal Necrolysis (TEN), which is also known as Lyell?s syndrome, is a widespread, life-threatening, mucocutaneous disease that is particularly observed secondary to drug-taking and less commonly secondary to infections and immunization. Carbamazepine is associated with benign pruritic rash in 10-15% of the patients, but the life threatening dermatological syndromes like exfoliative dermatitis, erythema multiforme, the Stevens-Johnson Syndrome (SJS) and TEN are rarely seen with the carbamazepine treatment. The 32 year old female who suffering from chronic backache, who was prescribed carbamazepine along with an intravenous combination of vitamin B-complex and calcium, developed fever, cough and mucocutaneous manifestations of TEN after 15 days of the treatment. She was treated in the hospital with systemic steroids, intravenous immunoglobulins, antibiotics, intravenous fluids and supportive care. In spite of the above treatment, the patient could not survive for more than seven days.
机译：毒性表皮坏死症（TEN），也称为Lyell's综合征，是一种广泛的，威胁生命的粘膜皮肤疾病，在吸毒之后尤其是继发于感染和免疫之后尤其明显。卡马西平在10-15％的患者中伴有良性瘙痒性皮疹，但是使用卡马西平治疗很少见到危及生命的皮肤病综合症，例如剥脱性皮炎，多形性红斑，史蒂文斯-约翰逊综合症（SJS）和TEN。这位患有慢性腰痛的32岁女性，在服药15天后，服用卡马西平以及维生素B复合物和钙的静脉内联合治疗，出现发热，咳嗽和粘膜皮肤表现。她在医院接受了全身性类固醇，静脉内免疫球蛋白，抗生素，静脉内输液和支持治疗。尽管进行了上述治疗，患者仍无法存活超过7天。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号