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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Nasal Discharge Cytology an Important Diagnostic Method for Allergic Fungal Sinusitis: Report of Three Cases
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Nasal Discharge Cytology an Important Diagnostic Method for Allergic Fungal Sinusitis: Report of Three Cases

机译:鼻放电细胞学是过敏性真菌性鼻窦炎的重要诊断方法:三例报告

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Allergic fungal sinusitis (AFS) is a distinct clinicopathological entity. It occurs in immunocompetent individuals with history of atopy, increased IgE levels and peripheral eosinophilia and causes noninvasive pansinusitis. It is histologically characterised by the presence of ?allergic mucin? with clusters of eosinophils, charcot ? Leyden crystals and scattered fungal hyphae. AFS is an immunological reaction to fungal deposits. As AFS is noninvasive, fungal hyphae can be demonstrated in nasal secretions on cytology. Etiological agent of AFS is Aspergillus or pigmented dematiaceous family. Special stains are helpful for identification. We came across three cases of age group ranging from 26 to 60-year of recurrent rhinitis with nasal discharge. The nasal secretions were collected by nasal swabs onto the glass slide and stained with Giemsa and silver stains. Smears revealed fungal hyphae amidst inflammatory cells with occasional Charcot-Leyden crystals. Nasal secretion cytology plays an important role in diagnosis and can be used for preoperative as well as intraoperative diagnosis of AFS and can be used as an additional diagnostic tool.
机译:过敏性真菌性鼻窦炎(AFS)是独特的临床病理学实体。它发生在具有特应性病史,IgE水平增高和外周嗜酸性粒细胞增多的具有免疫能力的个体中,并引起无创性全神经炎。其组织学特征是“过敏性粘蛋白”的存在。与嗜酸性粒细胞簇,夏科?莱顿晶体和分散的真菌菌丝。 AFS是对真菌沉积物的免疫反应。由于AFS是非侵入性的,因此在细胞学上的鼻分泌物中可以显示出真菌菌丝。 AFS的病原体是曲霉属或色素性皮肤病家族。特殊污渍有助于识别。我们遇到了3例年龄在26至60岁的鼻炎复发鼻炎患者。通过鼻拭子将鼻分泌物收集到载玻片上,并用吉姆萨和银染剂染色。涂片显示炎性细胞中有真菌菌丝,偶有夏科特-莱登晶体。鼻分泌细胞学在诊断中起着重要作用,可用于AFS的术前和术中诊断,并可作为其他诊断工具。

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