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Effects of Gestational Diabetes Mellitus on Umbilical Cord Morphology: A Comparative Study

机译:妊娠期糖尿病对脐带形态的影响:比较研究

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Gestational Diabetes Mellitus (GDM) has great effects on umbilical cord gross morphology. Antenatal detection of altered morphology would be helpful to identify the impact of GDM on umbilical cord to reduce fetomaternal complications.Aim: To assess and compare the morphological features of umbilical cord among gestational diabetic and normal subjects.Materials and Methods: The study was conducted in the Department of Anatomy, PK Das Institute of Medical Sciences Palakkad, Kerala, India. The subjects included in this present study were divided into two groups. Group I consisted of normal non-diabetic pregnant women (n=52) and group II consisted of mothers with GDM (n=59). A total of 111 placentas along with the umbilical cord were collected and morphological parameters of umbilical cord such as length, diameter, circumference, coiling index, insertion, knots and number of vessels were noted. Descriptive statistical analysis was done using the statistical software SPSS version 23.0.Results: Mean diameter (1.303±0.1884) and circumference (4.073±0.595) were found more in GDM mothers than normal (1.163±0.1815 and 3.648±0.5952) which was statistically significant (p-value 0.0001). No significant changes were observed in length, coiling index, mode of insertion and false knots among GDM and normal. The number of umbilical cord vessels was same in both the groups and true knots were absent.Conclusion: Knowledge about the variation in the morphometric measurements of umbilical cord is important for the early detection of the maternal complications and to prevent the adverse fetal outcome.
机译:妊娠糖尿病(GDM)对脐带总体形态有很大影响。产前检测形态改变有助于确定GDM对脐带的影响,以减少胎儿母系并发症。目的:评估和比较妊娠糖尿病患者和正常人的脐带形态特征。材料与方法:这项研究是在印度喀拉拉邦帕拉卡德PK达斯医学科学研究所的解剖学系中进行的。本研究包括的受试者分为两组。第一组由正常的非糖尿病孕妇组成(n = 52),第二组由患有GDM的母亲组成(n = 59)。总共收集了111个胎盘以及脐带,记录了脐带的形态参数,例如长度,直径,周长,卷曲指数,插入,结和血管数量。使用统计软件SPSS 23.0版进行描述性统计分析。结果:发现GDM母亲的平均直径(1.303±0.1884)和周长(4.073±0.595)比正常人(1.163±0.1815和3.648±0.5952)多。具有统计学意义(p值0.0001)。在GDM和正常人之间,长度,卷曲指数,插入方式和假结没有观察到明显变化。两组中的脐带血管数量相同,并且没有真正的结。结论:了解脐带形态测量值的变化对于早期发现母体并发症和防止胎儿不良至关重要结果。

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