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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Syphilis Screening in Pre-procedural Patients at a Tertiary Cardiac Care Centre in India
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Syphilis Screening in Pre-procedural Patients at a Tertiary Cardiac Care Centre in India

机译：在印度三级心脏护理中心对术前患者进行梅毒筛查

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Routine pre-procedural screening for blood-borne infections is a common practice despite lack of standard guidelines. The incidence of syphilis has shown an upward trend in recent years.Aim: To determine the prevalence and clinical significance of routine screening for syphilis in pre-procedural patients in tertiary care cardiac centre.Materials and Methods: This prospective study included consecutive patients undergoing surgical and percutaneous invasive procedures at a tertiary cardiac care centre from March 2017 to August 2017. All patients were screened for syphilis using ELISA for detection of Treponema pallidum IgG antibodies. All patients who were positive for ELISA were confirmed with Treponema pallidum Haemagglutination Assay (TPHA).Results: A total of 13,865 patients were screened and the seropositive rate was 0.45%. Most patients were in the age group of 51-70 years (71.4%) and were male (76.2%). Three patients had manifestation of cardiovascular syphilis and two patients were positive for HIV also. There was no reported incidence of needlestick injury or mucus membrane exposure to blood products during the procedures.Conclusion: Routine pre-procedural screening for syphilis is not beneficial due to low seroprevalence. Screening must be limited to at risk individuals.
机译：尽管缺乏标准指南，常规的术前筛查血源性感染仍是一种普遍做法。梅毒的发病率近年来呈上升趋势。目的：确定三级医疗中心手术前患者常规筛查梅毒的患病率及其临床意义。材料与方法：这种前瞻性研究包括从2017年3月至2017年8月在三级心脏护理中心接受手术和经皮侵入性手术的连续患者。所有患者均使用ELISA筛查梅毒，以检测梅毒螺旋体IgG抗体。所有的ELISA阳性患者均通过梅毒螺旋体血凝试验（TPHA）进行了确诊。结果：共筛查了13865例患者，血清阳性率为0.45％。大多数患者处于51-70岁年龄段（71.4％），其中男性（76.2％）。 3例表现为心血管梅毒，2例HIV阳性。在手术过程中，没有发生针刺损伤或粘膜接触血液制品的报道。结论：由于低血清阳性率，对梅毒进行常规的术前筛查是无益的。筛选必须仅限于有风险的个人。

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