Examination of the Borrelia burgdorferi Transcriptome in Ixodes scapularis during Feeding

Sukanya Narasimhan; Felix Santiago; Raymond A. Koski; Brandon Brei; John F. Anderson; Durland Fish

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Examination of the Borrelia burgdorferi Transcriptome in Ixodes scapularis during Feeding

机译：进食过程中肩I小体疏氏疏螺旋体转录组的检查

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Borrelia burgdorferi gene expression within the guts of engorging Ixodes scapularis ticks was examined by use of differential immunoscreening and differential expression with a customized amplified library. Fourteen chromosomal genes involved in energy metabolism, substrate transport, and signal transduction and 10 (4 chromosomal and 6 plasmid) genes encoding putative lipoproteins and periplasmic proteins were preferentially expressed in engorging ticks. These data demonstrate a new approach to the global analysis of B. burgdorferi genes that are preferentially expressed within the vector during feeding.

机译：通过差异免疫筛选和定制化扩增文库的差异表达，检查了吞噬肩I小tick虫肠道内的 Borrelia burgdorferi 基因表达。参与能量代谢的14个染色体基因和编码推定脂蛋白和周质蛋白的10个基因（4个染色体和6个质粒）被优先表达。这些数据证明了对 B进行全局分析的新方法。饲喂期间优先在载体内表达的burgdorferi 基因。 展开▼

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《Journal of bacteriology》 |2002年第11期|共4页

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Sukanya Narasimhan; Felix Santiago; Raymond A. Koski; Brandon Brei; John F. Anderson; Durland Fish;
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中图分类微生物学;

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1. Novel Borrelia burgdorferi isolates from Ixodes scapularis and Ixodes dentatus ticks feeding on humans. [J] . J F Anderson, R A Flavell, L A Magnarelli, Journal of Clinical Microbiology . 1996,第3期

机译：新颖的伯氏疏螺旋体分离自肩x龙虾和齿叉龙tick，它们取食于人类。

2. Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA [J] . Maggi Ricardo G., Toliver Marcee, Richardson Toni, Ticks and tick-borne diseases . 2019,第2期

机译：博尔德里亚布尔戈多利，Borrelia Bissettiae和Bartonella Henselae的区域普及，Ixodes Pacificus和Uxodes Scapularis在美国

3. Comparison of Tick Feeding Success and Vector Competence for Borrelia burgdorferi Among Immature Ixodes scapularis (Ixodida: Ixodidae) of Both Southern and Northern Clades [J] . Goddard Jerome, Embers Monica, Hojgaard Andrias, Journal of Medical Entomology . 2015,第1期

机译：南部和北部进化枝未成熟的肩x小Bor（Ixodida：Ixodidae）的伯氏疏螺旋体（Borrelia burgdorferi）的ick饲成功和媒介能力的比较

4. PREVENTION OF BORRELIA BURGDORFERI AND ANAPLASMA PHAGOCYTOPHILUM TRANSMISSION FROM IXODES SCAPULARIS TO DOGS BY SAROLANER [C] . Nicole Honsberger, Robert Six, Thomas Heinz, Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：预防贝罗莱亚伯格多利和Anaplasma吞噬粒子从Ixodes Scapularis到Sarolaner的狗

5. Comparative population genetics of Lyme disease spirochete (Borrelia burgdorferi) and its tick vector (Ixodes scapularis) in the United States. [D] . Qiu, Wei-Gang. 1999

机译：在美国，莱姆病螺旋体（Borrelia burgdorferi）及其壁虱载体（Ixodes scapularis）的比较种群遗传学。

6. Examination of the Borrelia burgdorferi Transcriptome in Ixodes scapularis during Feeding [O] . Sukanya Narasimhan, Felix Santiago, Raymond A. Koski, 2002

机译：进食过程中肩I小体疏氏疏螺旋体转录组的检查

7. Examination of the Borrelia burgdorferi Transcriptome in Ixodes scapularis during Feeding [O] . Narasimhan, Sukanya, Santiago, Felix, Koski, Raymond A., 2002

机译：进食过程中肩I小体疏氏疏螺旋体转录组的检查

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4. 硬皮病与布氏疏螺旋体感染有关的证据 [J] . 鲍迎秋 ,傅裕 ,常建民 . 中国麻风皮肤病杂志 . 2002,第002期

5. 聚合酶链反应检测进行性特发性皮肤萎缩中博氏疏螺旋体DNA [J] . 马东来 ,周光霁 . 中华皮肤科杂志 . 1996,第006期

6. 《儒藏》本陈奂《诗毛氏传疏》校点勘误五则 [C] . 孙赫男 . 第三届中国文学博士后论坛 . -1

7. 伽氏疏螺旋体P66基因的特征与抗原性研究 [A] . 于培发 . 2016

1. 伽氏疏螺旋体OspA蛋白C端肽段及其应用 [P] . 中国专利： CN110483624A . 2019-11-22

2. 一种伽氏疏螺旋体多克隆抗体及应用 [P] . 中国专利： CN106432487A . 2017-02-22

3. Tick (Ixodes scapularis) vector saliva-induced Lyme disease spirochete (Borrelia burgdorferi) antigens as vaccine candidates [P] . 外国专利： US6312915B1 . 2001-11-06

机译：ick虫（肩x）载体唾液诱导的莱姆病螺旋体（Borrelia burgdorferi）抗原作为候选疫苗

4. TICK (IXODES SCAPULARIS) VECTOR SALIVA-INDUCED LYME DISEASE SPIROCHETE (BORRELIA BURGDORFERI) ANTIGENS AS VACCINE CANDIDATES [P] . 外国专利： EP0880543A4 . 2000-08-02

机译：ICK虫（粘液囊尾IX）矢量唾液诱导的莱姆病螺旋体（鲍氏疏螺旋体）抗原作为疫苗候选者

5. TICK (IXODES SCAPULARIS) VECTOR SALIVA-INDUCED LYME DISEASE SPIROCHETE (BORRELIA BURGDORFERI) ANTIGENS AS VACCINE CANDIDATES [P] . 外国专利： EP0880543A1 . 1998-12-02

机译：ICK虫（粘液囊尾IX）矢量唾液诱导的莱姆病螺旋体（鲍氏疏螺旋体）抗原作为疫苗候选者

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Examination of the Borrelia burgdorferi Transcriptome in Ixodes scapularis during Feeding

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