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首页> 外文期刊>Scientific reports. >No Prophylactic Antibiotic Use for Young Children’s Intussusception with Low-risk Infection after Successful Air Enema Reduction
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No Prophylactic Antibiotic Use for Young Children’s Intussusception with Low-risk Infection after Successful Air Enema Reduction

机译：在成功的空气灌肠后，没有预防性抗生素用于幼儿的肠胃肠溶蛋白酶肠溶性抗生素酶活性

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The Chinese government has issued the policy of promulgating the clinical use of antibacterial drugs since 2011. Prophylactic antibiotic use is a challenging problem among young children with intussusception after successful air enema reduction. There were limited data regarding the clinical value of prophylactic antibiotics for intussusception with low-risk infections. A retrospective non-randomized comparative study was conducted among 188 young children with intussusception after successful air enema reduction between January 1, 2011 and December 30, 2013. Among these children, 51 received prophylactic antibiotics and 137 did not receive antibiotics. Our results showed that there were no significant differences in age, gender, weight, admission period, reduction interval, axillary temperature, leukocytes, neutrophils, lymphocytes, monocytes, mesenteric lymph nodes and complications between groups (P??0.05). The national policy had significantly improved clinical use of antibiotic for young children with low-risk intussusception (OR??0.001, P??0.001). Inpatients days were longer for children used antibiotics than those who did not (median, 27.0?hours vs 21.0?hours, P?=?0.003). Prophylactic antibiotics appeared to be of little value after the successful air enema reduction of intussusception in young children with low-risk infection. Policy intervention is effective for antibiotic use in China.
机译：中国政府自2011年以来发布了促进抗菌药物的临床应用的政策。预防性抗生素使用是在成功的空肠减少后进行肠胃肠道患儿的幼儿存在挑战性问题。关于预防性抗生素的肠套型感染的临床价值存在有限的数据。在2011年1月1日至2013年12月30日期间，在成功的空中灌肠后，在188名幼儿中进行了回顾性的非随机比较研究。在这些儿童中，51名接受预防性抗生素和137名没有接受抗生素。我们的研究结果表明，年龄，性别，体重，入学期，减少间隔，腋生温度，白细胞，中性粒细胞，淋巴细胞，单核细胞，肠系膜淋巴结，肠系膜淋巴结和组之间并发症的巨大差异（P？>？0.05）。国家政策显着改善了患有低风险性肠蛋型肠蛋虫的患儿抗生素的临床应用（或？<？0.001，P？<〜0.001）。儿童使用抗生素比那些没有（中位数，27.0？小时vs 21.0？小时，p？0.003）的儿童使用抗生素的时间更长。预防性抗生素在患有低风险感染的幼儿中的肠胃灌肠后胰灌肠后似乎重视。政策干预对于中国的抗生素使用是有效的。

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