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首页> 外文期刊>BMC Family Practice >Incident somatic comorbidity after psychosis: results from a retrospective cohort study based on Flemish general practice data
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Incident somatic comorbidity after psychosis: results from a retrospective cohort study based on Flemish general practice data

机译：精神病后的事件躯体合并症：基于佛兰芒一般实践数据的回顾性队列研究结果

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Background Psychotic conditions and especially schizophrenia, have been associated with increased morbidity and mortality. Many studies are performed in specialized settings with a strong focus on schizophrenia. Somatic comorbidity after psychosis is studied, using a general practice comorbidity registration network. Methods Hazard ratios are presented resulting from frailty models to assess the risk of subsequent somatic disease after a diagnosis of psychosis compared to people without psychosis matched on practice, age and gender. Diseases studied are cancer, physical trauma, diabetes mellitus, gastrointestinal disorders, joint disorders, irritable bowel syndrome, general infections, metabolic disorders other than diabetes, hearing and vision problems, anemia, cardiovascular disease, alcohol abuse, lung disorders, mouth and teeth problems, sexually transmitted diseases. Results Significant higher risks after a diagnosis of psychosis were found for the emergence of diabetes, physical trauma, gastrointestinal disorders, alcohol abuse, chronic lung disease and teeth and mouth problems. With regard to diabetes, by including the type of antipsychotic medication it is clear that the significant overall effect was largely due to the use of atypical antipsychotic medication. No significant higher risk was seen for cancer, joint conditions, irritable bowel syndrome, general infections, other metabolic conditions, hearing/vision problems, anaemia, cardiovascular disease or diabetes, in case no atypical antipsychotic medication was used. Conclusion Significantly higher morbidity rates for some somatic conditions in patients with psychosis are apparent. People with a diagnosis of psychosis benefit from regular assessments for the emergence of somatic disorders and risk factors, including diabetes in case of atypical antipsychotic medication.
机译：背景技术精神病和尤其是精神分裂症，都与发病率和死亡率增加有关。许多研究是在专业设置中进行，具有强烈关注精神分裂症。研究精神病后的体重率，采用一般实践合并器登记网络研究。方法危害比率由脆弱的模型提出，评估后期细胞疾病后的风险，而在没有精神病的人们与实践，年龄和性别相匹配。研究的疾病是癌症，物理创伤，糖尿病，胃肠疾病，关节障碍，肠易感染，一般感染，糖尿病以外的代谢障碍，听力和视力问题，贫血，心血管疾病，酒精滥用，肺病紊乱，嘴巴和牙齿问题， 性传播疾病。结果发现糖尿病，物理创伤，胃肠道疾病，酒精滥用，慢性肺病和牙齿和牙齿问题诊断后，发现精神病诊断后的风险显着较高。关于糖尿病，通过包括抗精神病药的类型，显然，显着的整体效果主要是由于使用非典型抗精神病药。对于癌症，关节条件，肠易激综合征，一般感染，其他代谢条件，听力/视觉问题，贫血，心血管疾病或糖尿病，没有显着较高的风险，以防不使用非典型抗精神病药。结论精神病患者的一些躯体病症的发病率显着较高。诊断精神病的人们从定期评估中受益于躯体障碍和危险因素的出现，包括糖尿病，以防非典型抗精神病药。

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